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Lipitor
Atorvastatin
Crestor
Rosuvastatin
Zocor
Simba statin
Lescol
Fluvastatin
Altoprev
Lovastatin
Livalo
Pitavastatin
Pravachol
Pravastatin
Praluent
Alirocumab
Evolocumab
Repatha
Welchol
Colesevelam
Prevalite
Cholestyramine
Lopid
Gemfibrozil
Tricor
Fenofibrate
Lovaza
Omega 3 ethyl esters
Vascular
Icosapent ethyl
Drugs that can increase LDL (not TG)
SGLT2 inhibitor
Pioglitazone
Fibrates
Fish oils
Drugs that increase TG (not LDL)
IV Lipids
Propofol
Alcohol
Bile Acid Sequesterants
Main side effects of statins
HMG
Hepatoxic, Myalgia, Glucose (increase)
Which other cholesterol meds should you NOT use with Zetia
Don’t use Gemfibrozil or fenofibrates
Which bile acid sequester-ant is OK in pregnancy
Pregnancy
Contra indications of bile acid sequesterants
Bowel obstruction, biliary obstruction, TG >500
Which classes mainly used to reduce triglycerides
Fibrates, Niacin, Fish Oils
If you have a statin which cholesterol med should you avoid adding
Fibrates like Gemfibrozil or the others
Which lipid lowering agents are hepatotoxic as hell
Statins
Zetia
Gemfibrozil
Niacin
Preferred initial treatments for hypertension
Thiazides
DHP-CCBs
ACE/ARB
With what BP would you start combination therapy
>20/10 over goal (150/90)
Benicar HCT
Olmesartan/HCTZ
Diovan HCT
Valsartan/HCTZ
Exforge
Valsartan/Amlodipine
Hyzaar
Losartan/HCTZ
Ziac
Bisoprolol/HCTZ
Lotrel
Benazepril/Amlodipine
Zestoretic
Lisinopril/HCTZ
HTN agents in pregnancy whats safe
Labetolol, Nifedipine, Methyldopa
Thiazide : Contraindications and Side effects?
Sulfa allergy
Photosensitivity, impotence, GOUT
Where do Thiazides work
Distal convoluted tubule
Where does Acetazolamide work
Proximal convoluted tubule
Where do loop diuretics work
Ascending loop
Where does spironolactone work
Collecting duct
Where do SGLT-2 inhibitors work
Proximal tubule (like Acetazolamide)
Side effects of all CCBS
Peripheral edema, gingival hyperplasia
Non-DHP CCBS: are they + or - chronotropes? Inotropes
Negative both
Which antihypertensives to avoid in heart failure
Non-DHP CCBs
Cardizem
Diltiazem
Tiazac
Diltiazem
Calan
Verapamil
Lotensin
Benazepril
Vasotec
Enalapril
Zestril
Lisinopril
Quinapril
Accupril
Ramipril
Altace
Avapro
Irbesartan
Cozaar
Losartan
Benicar
Olmesartan
Diovan
Valsartan
CONTRAINDICATIONS for Spironolactone
Hyperkalemia
Renal disease
Addison’s
Heart failure beta blockers
BE MORE CHILL
Bisoprolol, Metoprolol, Carvedilol
Brevibloc
Esmolol
stable angina treatment approach mnemonic
ABCDE
ANTIPLATELT
BLOOD PRESSURE
CHOLESTEROL AND CIGARETTES
DIET AND DIABETES
EXERCISE AND EDUCATION
Which medication can increase oxygen supply in angina
CCB
Which class to avoid in Prinzmetal? Which is preferred
Avoid beta blockers
Yay CCBS are good
MOST COMMON DOSE FOR SHORT ACTING NITRATES?
0.4
Mnemonic for ACS treatment
MONA-GAP-BA
Clopidogrel what CYP genotype should you avoid it with
CYP2C19 poor metabolizers
What class if Eptifbatide
Glycoproteins IIb/IIa antagonist
What drug class is tirofiban
Glycoproteins IIb/IIa antagonist
LVEF of HFREF
below 40%
Mnemonic for drugs that can worsen HF
DINATION
DPP 4
Immunosuppressant
NonDHP CCB
Antiarrythmics
Thiazoldinediones
Itraconazole
Oncology
NSAIDS
GDMT for Heart Failure with TARGET DOSES
Metoprolol = 200 mg daily
Carvedilol = 50 mg daily if IR, 80 if ER
Sprinolactone =25-50 mg daily
Eplereonone = 50 mg daily
SGLT-2s = 10 mg daily
Digoxin: Chronotropy vs Inotropy
Positive inotrope, negative chronotrope
Treatment for meningitis
Ceftriaxone (or Cefotaxime) plus Vanco (Add Ampicillin for listeria if neonate or old/immumocompromised)
When to treat otitis media vs observe (in kids)
Always treat if patient is < 6 months
Treat if 2 years of older if severe symptoms
And in-between those treat if symptoms are bilateral
1st like treatment for otitis media with dose? What if allergy?
Amoxicillin or Augmentin 90 mg/kg/day. If allergy do 3rd gen ceph
Treatment for acute sinusitis
Augmentin
Treatment for bronchitis
Nothing
Treatment for whooping cough
Macrolides
When to treat bacterial COPD exacerbation and what to use
Three cardinal symptoms: dyspnea, sputum volume and purulence
treat with Augmentin can also do Z pack, doxy, or respiratory quinolone
CAP treatment with no comorbidites
Amox, Doxy, or macrolide
CAP treatment with comorbidities
Beta Lactam + Macrolide or Doxy
FQ mono therapy
Severe inpatient CAP treatment
Beta Lactam + Macrolide OR
Beta Lactam + FQ
Anti pseudomonas beta Lactam
Cefepime
Meropenem
Zosyn
Aztreonam
Treatment for HAP/VAP
Start with base of MSSA coverage: Cefepime, Zosyn, Levo for example
Add vanco/linezolid if MRSA risk
Add 2nd antipseudomonal if been hospitalized for 5 days or more before onset (Don’t do 2 beta Lactams, mix it up)
Active TB treatment
RIPE x 2 months, then just RI
Rifampin
Isoniazid
Pyrazinamide
Ethambutol
Pyridoxine
Vitamin B 6
Infective Endocarditis Prevention
Amoxicillin 2 grams
Azithro/Clarithro 500 mg
Doxycycline 100
Treatment for SBP
Ceftriaxone, can consider carbapenems as alternative
2nd art prophylaxis for SBP
Bactrim or FQ
Outpatient SSTI treatment
Keflex, Bactrim, Doxy
Necrotizing fasciitis treatment
Zosyn or Meropenem
Plus Vanco or Dapto
Plus Clindamycin
UTI treatment in pregnancy
Augmentin or Keflex
Acute Cystitis treatment options and when to use each
Macrobid (don’t use in renal impairment)
Bactrim (don’t use if sulfa)
Fosfomycin is ok
Pyelonephritis treatment
Cipro + Levo
C. DIFF treatments and options (how long to use)
Treat for 10 days
1.) Fidoxamicin (Dificid)
2.) Vanco
3.) Metronidazole
If fulminant do Vanco + Flagyl
Symptoms of Chlamydia + Treatment
Genital Discharge
Doxy (if pregnant do Azithro)
Symptoms of gonorrhea + treatment
Genital discharge. Treat with Keflex (if you haven’t ruled out chlamydia then do doxy too)
Symptoms of Genital Warts and treatment
Single or multiple pink lesions
Imiquimod
Symptoms of Syphyllisand treatment
Painless smooth sores
Penicillin G 2.4 units IM
Symptoms of BV and treatment
Vaginas discharge with FISH, pH>4.5, little to no pain
Flagyl
Trichomoniasis symptoms and treatment
Yellow/green frothy discharge, pH >4.5, painful
Flagyl
Treatment for tick borne disease
Doxy (even if kids)