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Rifampicin
Inhibits RNA synthesis
Rifampicin
Causes Orange/Red discoloration
Isoniazid
Inhibits synthesis of Mycolic acid
Isoniazid
Causes Peripheral Neuropathy (Vit. B6)
Pyrazinamide
Unknown moa
Pyrazinamide
Hepatotoxic effect
Ethambutol
Inhibit incorporation of Mycolic acid & RNA synthesis
Ethambutol
Optic neuritis (Red & Green blindness)
Streptomycin
Effective for extracellular bacilli
Streptomycin
Vestibulotoxic effect