CVS - 14. Rheumatic Fever

What is the other name for Streptococcus pyogenes?

Group A beta-hemolytic streptococci (GABHS)

What is the infection that precedes rheumatic fever?

Streptococcal pharyngitis

What is the test used to document history of antecedent GABHS infection in rheumatic fever?

ASO titer

What is the mechanism of damage in rheumatic fever?

Type II hypersensitivity

What is the most common initial presentation of rheumatic fever?

Polyarthritis

What is the most specific presentation of rheumatic fever?

Sydenham chorea

What is the most serious presentation of rheumatic fever?

Carditis

What is the pathologic lesion in rheumatic heart disease?

Aschoff bodies

What is the name for the plump activated macrophages in Aschoff bodies in rheumatic heart disease?

Anitschkow cells/caterpillar cells

The lesions in rheumatic heart disease can be found in

all three layers of the heart (pancarditis)