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RNA-dependent RNA polymerase

what converts negative sense RNA to positive sense RNA?

Reovirus

RNA GENERALITIES

All RNA viruses are SINGLE STRANDED except

Retrovirus

Influenza virus

RNA GENERALITIES

All RNA viruses replicate in the CYTOPLASM except

Arenavirus

Bunyavirus

Paramyxovirus

• measles, mumps, rsv, parainfluenza

Orthomyxovirus

• influenza a & b

Filovirus

• ebola

Rhabdovirus

• rabies

NEGATIVE STRANDED RNA VIRUS

always bring polymerase or fail replication

Coltivirus - Colorado tick fever

Rotavirus - fatal diarrhea in children

Reovirus

Poliovirus - polio

Echovirus - aseptic meningitis

Rhinovirus - common cold

Coxsackievirus - aseptic meningitis, herpagina

HAV - acute viral hepatitis

Picornaviruses

PERCH

HEV

Hepevirus

Norovirus - viral gastroenteritis

Calciviruses

HCV

Yellow fever

Dengue

St. Louis Encephalitis

West nile virus - meningoencephalitis, flaccid paralysis

Zika virus

Flaviviruses (mosquitos)

Chikungunya virus - co-infection w/ dengue can occur

Rubella

Eastern and Western equine encephalitis

Togavirus

Toga CREW

HIV - AIDS

HTLV - T-cell leukemia

Retrovirus

Common cold

SARS

MERS

Coronavirus

Influenza virus

Orthomyxoviruses

Parainfluenza - croup

RSV - bronchiolitis in babies

Measles

Mumps

Paramomyxoviruses

Rabies

Rhabdovirus

Ebola/Marburg - hemorrhagic fever (often fatal)

Filoviruses

LCMV - lymphocytic choriomeningitis virus

Lassa fever encephalitis - spread by rodents

Arenavirus

Hantavirus - hemorrhagic fever, pneumonia

California encephalitis

Sandfly/Rift Valley fevers

Crimean-congo hemorrhagic fever

Bunyavirus

HDV - defective virus; needs HBV to replicate

Deltavirus