Nervous System Organization, Neurons, and Synapses

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Flashcards covering the organization of the nervous system, neuron structure and function, types of membrane potentials, and synaptic transmission, based on the provided lecture notes. Flashcards are in FILL_IN_THE_BLANK style.

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53 Terms

1
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The 'Big Picture' of the Nervous System involves sensory input, integration, and __.

motor output

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Information gathered by sensory receptors about internal and external events is called __.

sensory input

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The interpretation of sensory input by the nervous system is known as __.

integration

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Activation of effector organs to produce a response is referred to as __.

motor output

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The __ consists of the brain and spinal cord, acting as the integration and command center.

Central Nervous System (CNS)

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The __ relays information to and from the CNS.

Peripheral Nervous System (PNS)

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Neurons that relay information towards the CNS are called __ neurons.

afferent

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__ neurons relay sensory information from the skin, skeletal muscles, and joints.

Somatic afferent

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__ neurons relay sensory information from internal organs.

Visceral afferent

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The __ division of the PNS consists of efferent neurons that relay information from the CNS to effector organs.

Motor (Efferent)

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Conscious control of skeletal muscles via somatic motor neurons is part of the __.

Somatic (Voluntary) Nervous System

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The __ regulates smooth muscle, cardiac muscle, and glands involuntarily.

Autonomic (involuntary) nervous system (ANS)

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The two subdivisions of the Autonomic Nervous System are the sympathetic and __ divisions.

parasympathetic

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__ are excitable cells that transmit electrical signals, are long-lived, and amitotic.

Neurons

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Cells that protect neuronal function, such as Schwann cells, are called __.

supporting cells

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The specialized part of the neurolemma for stimulus reception that conveys electrical signals toward the cell body are the __.

dendrites

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The structure that propagates a 'message' away from the cell body and arises from the axon hillock is the __.

axon

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__ produce a segmented protein-lipid sheath around most long or large-diameter axons, which functions to protect, nourish, insulate, and increase the speed of nerve impulse transmission.

Schwann cells

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Myelin sheath gaps between adjacent Schwann cells, where axon collaterals can emerge, are called __.

Nodes of Ranvier

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Dense collections of myelinated fibers are known as __.

white matter

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Mostly neuron cell bodies and unmyelinated fibers, characterized by slow information transfer, form __.

gray matter

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Neuron cell bodies grouped together in the CNS are called __.

nuclei

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Neuron cell bodies grouped together in the PNS are called __.

ganglia

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Bundles of axons grouped together in the CNS are called __.

tracts

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Bundles of axons grouped together in the PNS are called __.

nerves

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Neurons that transmit electrical impulses from sensory receptors toward the CNS are __ neurons.

Sensory (Afferent)

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Neurons that carry electrical impulses from the CNS to effectors are __ neurons.

Motor (Efferent)

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__ are association neurons that shuttle electrical impulses through CNS pathways; most are entirely within the CNS and unmyelinated.

Interneurons

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Neurons relay information by changes in their __.

resting membrane potential

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Ion channels that are always open are called __ channels.

leakage (non-gated)

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__ channels open with the binding of a specific chemical compound, such as a neurotransmitter.

Chemically gated (ligand-gated)

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Channels that open and close in response to changes in membrane potential are known as __ channels.

Voltage-gated

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When gated channels are open, ions diffuse quickly across the neurolemma along chemical concentration gradients and __.

electrical gradients

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Incoming short-distance signals, usually initiated in dendrites and propagated toward the neuron cell body, are called __.

graded potentials

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Long-distance signals along axons that are propagated to other cells are called __.

action potentials

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A reduction in membrane potential where the inside of the neuron becomes less negative than the resting potential, increasing the probability of producing a nerve impulse, is called __.

depolarization

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The membrane potential at which the electrical 'message' will be propagated along the axon is known as the __.

threshold potential

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During the repolarizing phase of an action potential, Na+ channels inactivate and slow voltage-sensitive __ gates open, allowing ions to exit the cell.

K+

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When some K+ channels remain open after repolarization, allowing excessive K+ efflux and causing an undershoot of the membrane potential, it is called __.

hyperpolarization

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The period during which an action potential ensures an all-or-none event and enforces one-way transmission of nerve impulses is the __.

absolute refractory period

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The CNS determines stimulus intensity by the __ of action potentials.

frequency

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A junction that mediates information transfer from one neuron to another neuron or to an effector cell is a __.

synapse

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The neuron that conducts impulses toward the synapse is the __ neuron.

presynaptic

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The neuron that transmits impulses away from the synapse is the __ neuron.

postsynaptic

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Chemical messengers used within the nervous system are called __.

neurotransmitters

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The fluid-filled space separating the presynaptic and postsynaptic neurons, ensuring unidirectional communication, is the __.

synaptic cleft

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When an action potential arrives at the axon terminal of the presynaptic neuron, voltage-gated __ channels open, leading to neurotransmitter release.

Ca2+

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Binding of neurotransmitter to postsynaptic receptors that open chemically-gated channels, leading to a local depolarization, results in an __.

excitatory postsynaptic potential (EPSP)

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When neurotransmitter binds to postsynaptic receptors that open channels for K+ or Cl–, causing the intracellular compartment to become more negative (hyperpolarize) and reducing the neuron's ability to produce an action potential, it is called an __.

inhibitory postsynaptic potential (IPSP)

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One or more presynaptic neurons transmitting impulses in rapid-fire order leads to __.

temporal summation

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A postsynaptic neuron being stimulated by numerous presynaptic neurons at the same time results in __.

spatial summation

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Neurotransmitter effects are terminated by reuptake through transport proteins, enzymatic degradation, or __.

diffusion away from the synapse

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The effect of a neurotransmitter (excitatory or inhibitory) is determined by the __ type of the postsynaptic neuron.

receptor