Biochem Lecture: Carbohydrates

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48 Terms

1

Is converted into glucose for your body to function

Carbohydrates

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2

Simple carbohydrates

Monosaccharides (single sugar), Disaccharides (dual/double sugar)

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Complex carbohydrates

Polysaccharides (many sugar)

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Monosaccharides chemical formula

C6H12O6

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Dextrose or blood sugar

1. Primary fuel for the body

2. Found in all disaccharides & polysaccharides.

Glucose

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6

Fruit sugar (sweetest)

1. Found in fruit, honey, syrup

2. Converts to glucose in the body

Fructose

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Part of lactose

1. Found in milk.

2. Converts to glucose in the body

Galactose

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8

Maltose – malt sugar

1. Glucose + Glucose

2. Found in germinating seeds & used in fermentation to produce malted beverages (beer, whiskey)

Maltose

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Table sugar

1. Glucose + Fructose

2. Refined from sugar beets & cane

Sucrose

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10

Milk sugar

1. Glucose + Galactose

2. Lactose intolerance – missing digestive enzyme needed to split into two monosaccharide parts to absorb it

Lactose

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Bonding of 2 monosaccharide

Condensation

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Separation of 2 monosaccharide

Hydrolysis

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Long chains of glucose are found in animals.

1. Stored in liver & muscles.

2. Helps maintain blood glucose and important source of “quick energy”, esp. during exercise (lasts only about 12 hrs)

Glycogen

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14

Long chains of glucose found in plants.

Cereal grains (wheat, rice, corn, etc.), legumes (beans & peas), and root vegetables (potatoes, yams)

Starch

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15

Mostly indigestible CHO; gums, mucilages, lignin

• Component of plant cell walls

• Classified according to solubility in water.

• Abundant in whole grains, legumes, fruits and vegetables

Fibers

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nonviscous;cellulose, lignins

Insoluble Fibers

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viscous & fermentable ; pectins, gums, mucilages

Soluble Fibers

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18

Process of Digestion

Mouth

Stomach

Small Intestines

Pancreas

Large Intestines

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19

Produced by Mouth

Salivary Amylase

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Produced by Pancreas

Pancreatic Amylase

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Produced by Large Intestines

Mainly gas (flatulence)

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Stored as glycogen-() in the liver () in the muscle

1/3 and 2/3

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Gluconeogenesis

Glucose made from protein

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What happens when carbohydrates are in excess?

Converted to fat

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Glucose Pyruvate + ATP are produced

Glycolysis

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Conversion of excess glucose into glycogen in the liver for storage

Glycogenesis

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Breakdown of glycogen to glucose

Glycogenolysis

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Conversion of non-carbohydrate source (amino acids) to glucose

Gluconeogenesis

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Conversion of carbohydrates to fatty acids

Lipogenesis

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Breakdown of fats to glucose for energy

Lipolysis

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These maintain glucose homeostasis.

Regulating hormones

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Primary hypoglycemic agent; uptake of glucose by cells

From beta cells

Insulin

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Primary hyperglycemic agent

From Alpha cells

Glucagon

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Autoimmune diabetes

Type 1 Mellitus Diabetes

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Acquired diabetes

Types 2 Mellitus Diabetes

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Complex carbohydrates & fibre may reduce the risk of:

-Heart disease

-Diabetes

-GI issues

-Cancer

-Obesity

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• Lower blood cholesterol by binding dietary cholesterol so less absorbed.

• Slow glucose absorption

• Slow transit of food through upper GI tract

• Holds moisture in stools, softening them.

• Lower risk of heart disease

• Lower risk of diabetes

Soluble Fibers

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• Increase fecal weight - helps form soft, bulky stools which improves G.I. motility & reduces risk of constipation, hemorrhoids, diverticulosis & colon cancer.

• Speed fecal passage through colon

• Provide bulk and feelings of fullness (satiety)

Insoluble Fibers

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Alternative sweeteners (Sugar Alcohol)

Mannitol, Sorbitol, Xylitol

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Alternative sweeteners (Artificial Sweeteners)

Aspartame, Sucralose

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Hyperglycemia

Increase in blood glucose concentration

160-180mg/dL

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Glucosuria

Glucose in the urine

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Hypoglycemia

Decrease in blood glucose concentration

50-55mg/dL

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A. low blood glucose

B. Symptoms of hypoglycemia

C. Relief of symptoms after glucose administration

Whipple’s triad

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45

DIABETIC COMA

Hyperglycemia above 400 mg/dL

Hypoglycemia below 60 mg/dL

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Sorbitol, Mannitol, Xylitol

0.5

0.7

1

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47

(Relative Sweetness)

Aspartame

Sucralose

200

600

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48

(Avg Amount to replace 1 tsp Sugar)

Aspartame

Sucralose

18 mg

6 mg

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