Respiratory Corticosteroid Intranasal Products

Indications:

seasonal rhinitis and prevention of reoccurrence of nasal polyps following surgical removal. Use in children is NOTindicated for all products!

Warning

Use caution in patients on systemic alternate-day corticosteroid treatment since HPA suppression likelihood may increase - local delivery can reduced the systemic glucocorticoid activity, some weak mineralocorticoid activity

MOA

drenal corticosteroids with basic glucocorticoid activity and actions - decreased inflammatory mediators

Metabolism

primarily in the liver for these agents, all are highly protein bound with excretion both via renal and fecal routes

Localized infections from Candida albicans is rare but if any infection occurs, anti-infective therapy must be used

Paitent Informaion

May dry and irritate the nasal mucosa, sneezing may occur, if problems persist after 3 weeks contact the MD, do not exceed recommended dosage, contact MD if exposed to chicken pox or measles