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Central Nervous System (CNS)
Brain and spinal cord.
Peripheral Nervous System (PNS)
All nervous system found outside of the brain and spinal cord, including cranial nerves, spinal nerves, ganglia, enteric plexus, and sensory receptors.
Ganglia
Group of neuronal cell bodies outside the central nervous system.
Nucleus
Group of neuronal cell bodies within the central nervous system.
Enteric plexus
Interconnections of neurons along the digestive tract, including the myenteric plexus and submucosal plexus.
Sensory receptors
Structures that receive sensation in viscera and skin, which can be part of or associated with a sensory neuron.
Somatic nervous system
We are consciously aware of the sensory input and the motor output.
Autonomic nervous system
We are not consciously aware of the sensory input and the motor output; it works automatically.
Sympathetic division
Part of the autonomic nervous system responsible for the 'Fight or flight' response.
Parasympathetic division
Part of the autonomic nervous system responsible for the 'Rest and digest' response.
Enteric nervous system
'Gut brain'; the interweaving of nerve fibers along the digestive tract.
Sensory neurons
Afferent neurons that transmit sensory information from the environment or internal organs to the CNS.
Somatic Sensory Neurons
Transmit conscious sensations to the CNS, involving sensations of touch, temperature, and pain.
Autonomic Sensory Neurons
Transmit unconscious sensations to the CNS, involving viscera sensations such as blood pressure and level of oxygen in the blood.
Exteroceptors
Sensory receptors located in the skin.
Proprioceptors
Sensory receptors located in muscles and joints.
Interoceptors
Sensory receptors located in visceral organs.
Integrative function
The process by which the central nervous system interprets sensory information and determines the appropriate outcome.
Motor neurons
Efferent neurons that transmit motor information from the CNS to the appropriate effectors (muscles and glands).
Somatic motor neurons
Control skeletal muscles consciously and transmit conscious motor commands from the CNS to skeletal muscles.
Autonomic motor neurons
Control smooth muscles, cardiac muscle, and glands, transmitting unconscious motor commands from the CNS.
Afferent neurons
Another name for sensory neurons, which carry sensory information to the CNS.
Somatic afferent neuron
A sensory neuron that allows us to become aware of sensations.
Autonomic afferent neuron
A sensory neuron that transmits sensations we do not become aware of.
CNS
Central Nervous System, which interprets sensory information.
Motor neuron
A neuron that exits the CNS to control muscle contraction or relaxation.
Efferent neuron
Another name for motor neurons, as they carry information away from the CNS.
Somatic motor neuron
A type of motor neuron used for conscious movement.
Autonomic motor neuron
A type of motor neuron that operates automatically, without conscious awareness.
Smooth muscle cells
Muscle cells found in the walls of blood vessels that affect blood pressure and heart rate.
Neurons
Highly specialized cells capable of communication and forming networks.
Number of neurons in the brain
Approximately 85 billion neurons.
Neuron communication
Each neuron communicates with 1,000 to 10,000 other neurons.
Dendrites
Branched extensions of the neuron that receive incoming signals.
Cell body (perikaryon/soma)
The part of the neuron that contains the nucleus.
Axon hillock
The point of no return in a neuron where the nerve impulse passes into the axon.
Axon
The branch of the neuron that takes information away from the cell body.
Terminal button
The end of the axon where neurotransmitters are stored.
Neurotransmitters
Chemical signals that transfer information from one neuron to another.
Electrical signals
Changes in voltage that travel through the neuron.
Chemical signals
Signals in the form of neurotransmitters that communicate between neurons.
Nerve Cells
Another term for neurons.
Nerve Fibers
Another term for neurons, emphasizing their long extensions.
Voltage change
The basis of electrical signals in neurons.
Lie detector
A device that uses autonomic responses like heart rate and blood pressure to detect deception.
Neuronal communication process
The sequence where electrical signals trigger neurotransmitter release, which then affects other neurons.
Nerve Impulse
Electrical signal and action potential are the same thing when we are talking about transmission of information along neurons.
Action Potential
Initiated by depolarization of the cell membrane, leading to the generation of an electrical impulse.
Depolarization
The process that occurs when a cell is not 'at rest', making the inside of the cell more positive compared to the outside environment.
Resting Membrane Potential
The state of a cell when it is 'at rest', characterized by a more negative charge inside compared to the outside environment.
Polarized Cell
A cell that is more negative on the inside compared to the outside environment.
Sodium/Potassium Active Pump
A mechanism that pumps 3 Na+ ions outside of the cell and 2 K+ ions inside the cell, using ATP for energy.
Excitable Cells
Cells capable of changing polarity, such as muscle cells and neurons, which can undergo depolarization and repolarization.
Depolarization and Repolarization
Fundamental processes involved in the generation of action potentials.
Gated Ion Channels
Channels that open and close to regulate ion flow across the cell membrane.
Voltage-Gated Ion Channel
A gated ion channel that opens in response to a change in voltage.
Ligand-Gated Ion Channel
A gated ion channel that opens in response to a ligand binding a receptor on the channel.
Voltage-Gated Na+ Channel
A voltage-gated ion channel that allows the passage of Na+ ions.
Voltage-Gated Ca+2 Channel
A voltage-gated ion channel that allows the passage of Ca+2 ions.
Ligand-Gated Na+ Channel
A ligand-gated ion channel that allows the passage of Na+ ions.
Synapse
The communication between neurons.
Electrical Signal
An action potential or nerve impulse that results from depolarization.
Resting Neuron
A neuron at resting membrane potential, which is negative inside relative to the outside.
Stimulus
An event that causes voltage-gated Na+ channels to open, leading to depolarization.
Positive Ions (Na+)
Ions that flow into the neuron during depolarization.
Terminal Buttons
The end of the axon where the electrical signal causes the opening of voltage-gated Ca2+ channels.
Voltage-gated Ca2+ Channels
Channels that open in response to an electrical signal, allowing calcium ions to flow into the terminal buttons.
Neurotransmitter Release
The process where vesicles filled with neurotransmitters fuse with the plasma membrane of the terminal button, releasing neurotransmitters into the synaptic gap.
Synaptic Gap
The gap between neurons where neurotransmitters flow and bind to receptors in the adjacent neuron.
Presynaptic Neuron
The neuron before the synaptic gap that sends the signal.
Postsynaptic Neuron
The neuron after the synaptic gap that receives the signal.
Ligand-gated Ion Channels
Channels that open when neurotransmitters bind to receptors, allowing the flow of ions across the plasma membrane.
Neurotransmitter
Chemicals that facilitate the transmission of information from one neuron to another.
Excitatory Neurotransmitters
Neurotransmitters that bind to receptors associated with ligand-gated Na+ channels, permitting Na+ to enter the postsynaptic cell, resulting in depolarization.
Inhibitory Neurotransmitters
Neurotransmitters that bind to receptors associated with ligand-gated Cl- channels, permitting Cl- to enter and K+ to exit the postsynaptic cell, resulting in hyperpolarization.
Acetylcholine
A neurotransmitter that is excitatory in skeletal muscle and inhibitory in cardiac muscle.
Adrenaline (Epinephrine)
A neurotransmitter that is excitatory in cardiac muscle (increases heart rate) and inhibitory on respiratory smooth muscle (relaxes smooth muscle in respiratory system).
Endorphins
Neurotransmitters with inhibitory effects, causing relaxation and sleepiness.
Narcotic Drugs
Substances that mimic the effects of endorphins (endogenous morphine).
Removal of Neurotransmitters
The process of terminating signal transmission by removing neurotransmitters from the synaptic cleft.
Reuptake
The process where neurotransmitters are taken back up into the presynaptic neuron for recycling.
Enzymatic Degradation
The breakdown of neurotransmitters into inactive metabolites by enzymes in the synaptic cleft.
Diffusion
The process where neurotransmitters diffuse into the nearby tissue fluid.
Myelinated Axon
An axon that has Schwann cells or oligodendrocytes wrapping around it, insulating segments of the axon.
Unmyelinated Axon
An axon that is bare, with nothing wrapping around it.
Myelin Sheath
The insulating layer formed by the wrapping of another cell around segments of the axon.
Node of Ranvier
The part of the axon that does not have another cell wrapped around it.
Saltatory Conduction
The jumping motion of electrical signals from one Node of Ranvier to the next, allowing faster signal transmission.
Conduction Velocity
Myelinated Neurons have a higher conduction velocity than unmyelinated neurons.
Nerve Impulse Speed (Unmyelinated)
Nerve impulses can travel as slowly as 0.5 meters per second.
Nerve Impulse Speed (Myelinated)
Nerve impulses can travel as fast as 130 meters per second.
Nerve Impulse Strength
Remains constant over time and distance, with no information lost regardless of the distance traveled.
Multipolar Neuron
A neuron with several branches leaving the cell body, including several dendrites and one axon.
Bipolar Neuron
A neuron with two branches leaving the cell body, one being a dendrite and the other an axon.
Unipolar Neuron
A neuron with a single branch that splits into two branches: one dendrite and one axon.
Interneurons
Multipolar neurons that connect other neurons within the nervous system.
Sensory Neurons (Special Senses)
Bipolar neurons that carry sensory information for special senses.
Sensory Neurons (Other Sensations)
Unipolar neurons that carry sensory information for sensations other than special senses.
Pseudounipolar Neuron
Another name for unipolar neurons, indicating a single branch that splits.
Pseudounipolar
A type of neuron that appears to have a single branch but originates from two branches during embryonic development.