Salmonella spp.: Serogrouping and serotyping

Clinical laboratory serogrouping (4)

1. Subgrouping based on Ag presentation

   1. O = Somatic

   2. H = flagellar

   3. Vi = Capsular

Most human infections are due to these H antigens in this order

A, B, C1, C2, D, E

D = typhoid fever

How to do clinical laboratory serogrouping

1. Do Vi testing first

2. If Vi present, boil for 15 minutes to get rid og Vi antigen

3. Test O antigen

Public health sterotyping (2)

1. Very discriminatory

   1. Helps pinpoint and trace outbreaks

How to write serotypes

Samonella enterica serotype Dublin