Antigen Presentation

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5 Terms

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What are the 3 steps

  1. Phagocytosis

  2. Clonal Selection

  3. Activation

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What cells are APC’s

macrophages, dendritic cells, B cells

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Phagocytosis

Pathogen enters host, APC engulfs pathogen and displays its antigenic fragments on MHC II markers

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Clonal Selection

APC travels to lymph node and binds to a complementary Th cell, activating it 

  • it’s selected → clondal selection

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Activation

Activtated Th cell can now initiate the adaptive immune response through humourla or cell mediated means