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What are the 3 steps
Phagocytosis
Clonal Selection
Activation
What cells are APC’s
macrophages, dendritic cells, B cells
Phagocytosis
Pathogen enters host, APC engulfs pathogen and displays its antigenic fragments on MHC II markers
Clonal Selection
APC travels to lymph node and binds to a complementary Th cell, activating it
it’s selected → clondal selection
Activation
Activtated Th cell can now initiate the adaptive immune response through humourla or cell mediated means