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heredity
transmission of traits from one generation to the next
variation
shows that offspring differ somewhat in appearance from parents and siblings
genetics
scientific study of heredity and hereditary variation
genes
units of heredity and are segments of DNA
chromosome inheritance
how do offspring acquire genes from parents
locus
gene location on a certain chromosome
asexual reproduction
one parents produces genetically identical offspring via mitosis
sexual reproduction
two parents give rise to offspring that have unique combinations of genes inherited from the two parents
unique combination of alleles
46 chromosomes
how many chromosomes are in human somatic cells
23 chromosomes
how many chromosomes are in 1 set of a somatic cell
reduction of chromosomes
important event that must occur during chromosome inheritance
karyotype
ordered, visual representation of the chromosomes in a cell
metaphase (most compact)
what stage cells are used for karyotyping
homologous chromosomes
2 chromosomes composing a pair (mom and dad)
have the same characteristics (genes)
also called autosomes
sex chromosomes
distinct from each other in their characteristics
represented as X and Y
determine the sex of the individual
XX
what is the sex chromosome combination for female
XY
what is the sex chromosome combination for male
ploidy
measure of the number of sets of chromosomes
diploid cell
cell that has 2 sets of each of its chromosomes
after DNA synthesis
all chromosomes are duplicated and each consists of 2 identical sister chromatids
gametes
haploid cells containing only 1 set of chromosomes
23
how many chromosomes in a human gamete
life cycle
generation to generation sequence of stages in the reproductive history of an organism
ferilization and meiosis
what stages alternate in sexual life cycles
sexual maturity
point where the ovaries and testes produce haploid gametes via meiosis
fertilization
where gametes (sperm and ovum) fuse to form a diploid zygote
zygote
diploid cell that develops into an adult organism
diploid dominant, haploid dominant, alternation of generations
3 categories of life cycles in multicellular organisms
diploid dominant
in animals
meiosis occurs during gamete formation
gametes are the only haploid cells
haploid dominant
most fungi and some protists
meiosis produces haploid cells that give rise to a haploid multicellular adult organism
the haploid adult carries out mitosis producing cells that will become gametes
alternation of generations
plants and some algae
life cycle includes both diploid and haploid multicellular stages
meiosis
reduces the number of chromosomes sets from diploid to haploid
takes place in two sets of divisions, meiosis I and meiosis II
meiosis I
meiosis division set that reduces the number of chromosomes from diploid to haploid
meiosis II
meiosis division set that takes the products of meiosis I and produces four haploid daughter cells
S phase
chromosomes are duplicated during interphase
resulting sister chromatids are held together at the centromere
centrosomes also duplicated
prophase I
chromosomes condense and the nuclear envelope fragments. homologous chromosomes bind firmly together along their length forming a tetrad. chiasmata form between non sister chromatids. crossing over occurs at the chiasmata
sprindle fibers emerge from the centrosomes
prometaphase I
homologous chromosomes are attached to spindle microtubules at the fused kinetochore shared by the sister chromatids
chromosomes continue to condense and the nuclear envelope disappears completely
metaphase I
homologous chromosomes randomly assemble at the metaphase plate where they are maneuvered into place by the microtubules
anaphase I
spindle fibers pull the homologous chromsomes apart. the sister chromatids are still attached at the centromere
telophase I and cytokinesis
sister chromatids arrive at the poles of the cell and begin to decondense
nuclear envelope forms around each nucleus and cytoplasm divided by a cleavage furrow
result is 2 haploid cells with each cell containing one duplicated copy of each homologoous chromosome pair
prophase II
sister chromatids condense
new spindel begins to form
nuclear envelope starts to fragment
prometaphase II
nuclear envelope disappears and the spindle fibers engage the individual kinetochores on the sister chromatids
metaphase II
sister chromatids line up at the metaphase plate
anaphase II
sister chromatids are pulled apart by the shortening of the kinetochore microtubules
nonkinetochore microtubules lengthen the cell
telophase II and cytokinesis
chromosomes arrive at the poles of the cell and decondense
nuclear envelope surround the four nuclei
cleavage furrow divide the two cells into four haploid cells
synapsis and crossing over, tetrads at the metaphase plate, separation of homologues
3 events in meiosis I that help distinguish between meiosis and mitosis
synapsis and crossing over
homologous chromosomes physically connect and exchange genetic information
occur in Prophase I
chiasmata
x shaped structures formed during meiosis where homologous chromsomes exchange genetic material
tetrads on the metaphase plate
at metaphase I of meiosis, paired homologous chromsomes (tetrads) are positioned on the metaphase plates
separation of homologues
at anaphase I of meiosis, homologous pairs move toward opposite poles of the cell
in anaphase II of meiosis, sister chromatids separate
independent assortment
each pair of chromosomes sorts its maternal and paternal homologues into daughter cells independently of the other pairs
crossing over
what produces recombinant chromosomes that carry genes derives from two different parents
produces genetic variation
what is the purpose of reshuffling genetic material in meiosis
behavior of chromosomes during meiosis and fertilization
what makes up for most of the variation that arise in each sexually reproducing generation
2^(23) or 8.4 million
how many combinations are there for each gamete in humans
random fertilization
the fusion of gametes that produces a zygote with any of the 70 trillion diploid combinations (in humans)
genetic variation
raw material for evolution by natural selection
mutations
original source of genetic variation
sexual reproduction
produces new combinations of variant genes, adding more genetic diversity