Rad Bio Ch. 33 WS

The sequence of events following high-level radiation exposure leading to death within days or weeks is called the _____________________.

Acute radiation syndrome

The _______________________ consists of acute clinical symptoms that occur within hours of exposure and continue for up to a day or two.

Prodromal period

During the __________________________, the subject is free of visible effects.

Latent period

The immediate response of radiation sickness is the ________________.

prodromal

The ________________ is characterized by a reduction in white cells, red cells, and platelets.

Hematologist syndrome

_____________ occurs principally because of severe damage to the cells lining the intestines.

GI death

The mean survival time for the Central nervous system syndrome is _____________.

0-3 days

The LD 50/60 is the dose of radiation to the whole body that causes __________ of irradiated subjects to die within ___________ days.

50%; 60

Acute radiation lethality follows a ___________________ dose-response relationship.

nonlinear, threshold

The mean survival time decreases as radiation dose ___________________________.

Increases

When only a part of the body is irradiated, a _______________ dose is required to produce a response.

higher

Normal skin consists of three layers: an outer layer called the __________________________, and intermediate layer called the _________________________, and a ________________ layer.

Epidermis, dermis, subcutaneous

Damage to the _______________________ results in the earliest manifestation of radiation injury to the skin.

basal cells

__________________ was perhaps the first observed biologic response to radiation exposure.

erythema

The ________________ are critically important target organs.

Human gonads

The stem cells of the ovaries are the ___________.

oogonia

The male stem cell is the _________________.

spermatogonia

Doses in excess of ____________________ could cause permanent sterility.

5 Gyt (5000 mGyt)

All cells of the hemopoietic system apparently develop from a single type of stem cell called a _______________________.

Pluripotential stem cells

The hemopoietic system consists of ____________________________, _________________________, and ______________________.

bone marrow, circulating blood, lymphoid tissue

The principal response of the hemopoietic system to radiation exposure is a _________________________ in the number of all types of blood cells in the circulating peripheral blood.

Decrease

The ______________________ and the _______________________ are the most radiosensitive cells in the body.

lymphocytes; spermatogonia