Untitled Flashcards Set

What are the three layers of the heart wall?

Epicardium, Myocardium, Endocardium

What does Poiseuille's Law describe?

The relationship between flow rate, pressure gradient, vessel radius, viscosity, and vessel length.

What is the significance of small changes in the radius of blood vessels according to Poiseuille's Law?

Small changes in radius lead to significant changes in blood flow.

What is the function of vein valves?

To prevent backflow of blood, particularly in the legs.

What roles do endothelial cells serve in the cardiovascular system?

They have anticoagulant and prothrombotic roles.

What is Deep Vein Thrombosis (DVT)?

A blood clot in a deep vein, usually in the leg, that can lead to pulmonary embolism.

Where does T-cell positive selection occur?

In the cortex of the thymus.

What happens to T-cells that bind too strongly to self-antigens during negative selection?

They are eliminated to prevent autoimmunity.

What are the functions of germinal centers in lymphoid organs?

Affinity maturation and class switching of B cells.

What are splenic venous sinusoids?

Open, leaky capillaries in the red pulp of the spleen that help maintain blood cell populations.