Robert Hooke (1665)
coined the word "cell"
found that they appeared as tiny compartments or small fitted rooms
Anton van Leeuwenhoek (1676)
observed tiny living organisms
called them "animalcules"
first observed red blood cells of animals and sperm cells
Robert Brown (1831)
observed and coined "nucleus" inside the cells
Matthias Schleiden (1838)
all plant parts are made up of cells
Theodor Schwann (1839)
all animal tissues are composed of cells
Rudolf Virchow (1858)
all cells come from pre-existing cells
"omnis cellila e cellula"
Three Postulates of Cell Theory
all living organisms are composed of one or more cells
the cell is the basic unit of life
all cells come from preexisting cells
Prokaryotic Cells
single-celled microorganisms whose cells lack a nucleus and other organelles
Eukaryotic Cells
multicellular cell or organism that possesses a clearly defined nucleus
Plant Cell Structure
similar in shape (mostly rectangular or cube shaped), larger than animal cells in size,
Animal Cell Structure
shape and size vary greatly from irregular to round shapes defined by function
Three Roles of Cells
produce energy
produce protein
reproduce / make more cells
Organelles that Produce Energy
mitochondria, cell membrane, vacuole and vesicle, lysosome
Organelles that Produce Protein
Nucleus, Ribosome, Endoplasmic Reticulum, Golgi Apparatus
ATP
adenosine triphosphate (ATP), energy-carrying molecule found in the cells of all living things
cell membrane
separates cell from outside
controls what enters or leaves the cell
phospholipid
makes the cell membrane; composed of phosphate head and lipid tail (composed of fatty and phosphoric acid)
cell membrane
recognizes signals and allows communication between cells
cytoplasm
jelly-like material holding organelles in place, full of protein
vacuole and vesicles
responsible for transporting materials around the cell
food and water storage
mitochondria
"powerhouse of the cell" makes ATP energy from cellular respiration (is double membraned)
ATP Formula
sugar + O₂ → ATP
lysosome
responsible for food digestion
garbage disposal and recycling
chloroplasts
make energy and glucose from sunlight through photosynthesis
Central Dogma of Biology
Nucleus: DNA → RNA → Ribosome → Protein → Vasicle → Golgi Apparatus → Vesicle → Cells
Nucleus
control center of the cell
protects DNA
DNA
contains genetic code, and instructions for building proteins
Structure of Nucleus
contains: nuclear membrane, nucleolus (ribosome factory), chromosomes
ribosomes
protein factories, some are free in the cytoplasm, some are attached to ER
Centrioles
help coordinate cell division in animal cells