Chapter 17.2: The Henderson-Hasselbalch equation:

The effectiveness of a buffer solution is based on two factors:

buffer capacity and effective pH range.

Buffer capacity refers to the

ability of the buffer solution to resist a change in pH when an acid or base is added. Buffer capacity is dependent on the concentration of HA and A−.

Buffers are most effective at pH values within

1 pH unit of the pKa of the buffer’s conjugate acid. The buffer′s pH range is Pka±1.

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