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Stratum spinosum
Irregularly shaped cells, several layers thick.
Melanocytes
Cells producing melanin for UV protection.
Basal cell carcinoma
Cancer from uncontrolled stratum basale cell division.
Squamous cell carcinoma
Cancer from uncontrolled stratum spinosum cell division.
Dermis
Layer of dense irregular connective tissue beneath epidermis.
Dermal papillae
Wavy layer creating fingerprints and increasing friction.
Papillary layer
Upper layer of dermis made of loose connective tissue.
Reticular layer
Lower dermis layer with collagen fiber bundles.
Functions of the skin
Protection, sensation, temperature regulation, excretion, vitamin D production.
Stratum corneum
Top layer of dead, keratinized cells, 20-30 thick.
Stratum lucidum
Thin, translucent layer in thick skin areas.
Stratum granulosum
Layer where cells flatten and accumulate keratin.
Stratum basale
Base layer where cells constantly divide.
Melanin
Pigment that protects against UV radiation.
Skin cancer
Uncontrolled cell division due to DNA mutation.
Melanoma
Cancer from uncontrolled melanocyte division.
Lines of cleavage
Collagen fiber arrangement important for surgical cuts.
Decubitus ulcers
Bedsores from restricted blood supply to skin.
Hypodermis
Subcutaneous layer connecting skin to underlying tissues.
Insulation
Function of hypodermis to retain body heat.
Nutrient storage
Hypodermis stores energy in fatty tissues.
Temperature regulation
Sweat and blood flow manage body heat.