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Pathophysiology
Study of functional changes in the body caused by injury, disorder, or disease
Disease
Functional impairment of cells, tissues, organs, or organ systems
Includes: injuries, disorders, illnesses, syndromes
Pathogenesis
Origination and development of illness or disease
from point at which disease process begins
to point when disease prevents itself
risk factors (modifiable vs non-modifiable)
Goal of study is to prevent disease or facilitate early diagnosis and intervention
Etiology
Precise cause of disease
Pathogen
Disease causing microorganism
Multifactorial
Having more than one cause
Idiopathic
No known cause
Nosocomial
Caused by an infection received in a healthcare environment
Iatrogenic
Caused inadvertently by medical treatment
Clinical manifestations
Presenting signs and symptoms of disease
Sign
Something that the provider can see on a patient
Symptom
Something that the patient feels and tells the provider
Subacute
Acute
Chronic
Remissions
Symptoms and signs getting better
Exacerbations
Worsening of signs or symptoms
Asymptomatic
No symptoms
Diagnosis
A label for a disease and is based on diagnostic criteria
Prognosis
Prediction of how one will process through the disease process. Morbidity vs mortality.
Mortality
Occurrence of death in a population
Morbidity
The state of being diseased or unhealthy
Individual health
Focuses on the whol person and the person’s perception of health and illness
Health
Perceived wholeness of body, mind, and spirit
Illness
A state of resulting in suffering or distress (unhealthy or deseased)
Incidence
Number of new cases in a population
Prevalence
Percentage of a population with a disease
Endemic
An expected disease in a population
Epidemic
Rates of a disease higher than expected
Pandemic
An epidemic spread across continents
Primary prevention
Prevention of a disease from occurring
Secondary prevention
Early detection of a disease by screening
Tertiary prevention
Rehabilitation of a patient to prevent complications or progression of disease
Evidence based practice
A way of caring for others that is cognizant of the most current research and knowledge in the health professions