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nutrition
intake of food, considered in relation to the body’s dietary needs
Good nutrition and a well balanced diet is a cornerstone of good health
Malnutrition is when a person’s diet does not provide the right balance of nutrients for good health
micronutrients
needed in tiny amounts compared to macronutrients
ug or mg
vitamins and minerals
Vitamin
any group of organic compounds which are essential for normal growth and nutrition and are required in small quantities in the diet because they can’t be synthesised by the body
small quantities = mg or ug per day
Deprivation leads to development for a clinical deficiency disease and abnormal metabolic signs
Restoration leads to a cure or prevents that disease and normalises metabolism
Roles of macronutrients
Carbohydrates:
energy source, control of glucose and insulin metabolism, cholesterol and triglyceride metabolism
Lipid (fats)
storing energy, regulation and cell signalling, insulating and protecting, aiding digestion
Proteins:
growth and maintenance of cells and tissues, gene expression, hormones, antibodies, digestion, muscle contraction and movement
Vitamin classification
Water soluble
Fat Soluble
Water soluble vitamins
B1
B2
B3
B5
B6
B7
B9
B12
Fat soluble vitamins
A
D
E
K
Vitamin B9: folate
folic acid, converts to folate
They transfer one carbon fragments in many biosynthetic and catabolic reactions
Metabolically closely related to B12
important at times of increased cell division: pregnancy and developing foetus
Deficiency leads to megaloblastic anaemia
folate and pregnancy
normal recommended daily intake is 200ug a day
400ug a day is recommended for pregnant women and first 12 weeks
vitamin D
a group of fat soluble compounds
Most important for humans: D3 and D2
Main source is sunlight
vitamin D deficiency
v high levels of deficiency worldwide
Deficiency causes rickets in children
Deficiency causes osteomalacia in adults
Vitamin D deficiency risk groups
older people
People not exposed to the sun
Breastfed infants/ breastfeeding mothers
People with darker skin
People with fat malabsorption issues
Vitamin B12
lack of B12 causes body to produce abnormally large red blood cells that can’t function properly→ megaloblastic anaemia
Most common B12 deficiency cause: pernicious anaemia
Can also be lack of dietary intake or absorption issues including interactions with common medication like proton pump inhibitors and metformin
B12 deficiency is common (1 in 10 for over 75s)
iron deficiency
common global issue including developed countries
leads to iron deficiency anaemia
Common causes:
heavy menstrual bleeding
Bleeding from GI tract
Inadequate dietary intake
Malabsorption issues
Hypocalcaemia
hypoparathyroidism
Vit D deficiency
Chronic liver disease
Chronic kidney disease
Acute kidney injury
Energy expenditure
basal metabolism = energy required to keep your body functioning at rest: energy used to activities such as maintaining body temperature and supporting vital systems