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DEA
responsible for controlled substances
OSHA
responsible for workplace safety
FDA
responsible for drug approval and monitoring
USP
used for guidance on the compounding and safe handling of hazardous materials
ISMP
promotes med safety by attempting to prevent medication errors through education and information; release guidelines like error-prone abbreviations
MedWatch
database to report adverse events and med errors
VAERS
report adverse events with vaccines
PMP
database used on a state basis to show was controlled susbtances were picked up, where and when
FAERS
database that holds all report to the FDA about ADE and med errors
MedMarx
database that looks at ADE reports by hospitals
-glutide drug class
GLP-1 agonist
-gliflozin drug class
SGLT-2 inhibitor
-sliptin drug class
DPP-4 inhibitor
FDA red book
drug pricing
FDA purple book
search of proprietary and nonprorpietary profucts to find interchangeable biological products
orange book
therapeutic equivalence
therapeutic equivalence lettering rating
A means therapeutically equivalent, B is not equivalent
-pril drug class
ACE
ACE ADE
cough, angioedema and hypotension
-sartan drug class
ARB
ARB ADE
dry cough less than ACE, angioedema and fatigue
antiarrythmics ADE
QT prolongation, dizzy, drowsy
common antiarrythmics
amiodarone, flecainide, lidocaine, quinidine, propafenone
common antiplatelet agents
aspirin, clopidogrel, prasugel, ticagrelor
-grel
antiplatelet agents
-lol drug class
beta blockers
beta blocker ADE
fatigue, bradycardia. bronchocontriction, depression
CCB ADE
peripheral edema, palpitations, drowsy, headache
-dipine drug class
CCB
digoxin drug class
cardiac glycoside
-statin drug class specific
HMG Co-A reductase inhibitor
-fib- drug class specific
fibric acid cholesterol lowering
-chole- drug class specific
bile acid sequestrants cholestrol lowering
PCSK9 inhibitors examples and drug class
cholesterol lowering
alirocumab (Praluent) and evolocumab (Repatha)
omega 3 fatty acid drug examples
icosapent ethyl (Vascepta) and omega-3-acid ethyl esters (Lovaza)
cholesterol lowering
-sala- drug class
anti-inflammatory for GI system (chrons or UC)
-idine drug class
H2 receptor antagonists
examples of mucosal protectants
misoprostol and sucarlfate
examples of rapid acting insulin
NovoLog, HumaLog and Apida (aspart, lispro and glulisine)
intermediate acting insulin examples
NPH
long acting insulin examples
glargine (Basaglar, Lantus, Toujeo) and determir (Levemir)
metformin is what drug class
biguanide
sulfonylureas ADE
hypoglycemia and weight gain
metformin ADE
diarrhea, N/V, lactic acidosis
sulfonylurea examples (3)
glimepiride, glyburide, glipizide
DDP-4 inhibitors ADE
joint pain, SJS and hypoglycemia
-glu/tide drug class
GLP-1 agonists
formulation of GLP-1 agonists
injection EXCEPT Rybelsus which is oral form of semglutide
SGLT2 ADE
UTI and yeast infections
ADE w short term steriod use
insomnia, mood changes, weight gain, sun sensititvity
ADE w long term steroid use
HTN, hyperglycemia, edema, osteoporosis, cataracts and infections
-dron/ate/ic drug class
bisphosphonates
-pram drug class
SSRI
-oxetine drug class
SSRI EXCPET duloxetine which is SNRI
-venlafaxine drug class
SNRI
common TCAs
amitriptyline, doxepin, imipramine, nortriptyline
antidote for BZD overdose
flumazenil (Romazicon)
when to take stimulants (ADHD)
in the morning
only stimulant not a CII
atomoxetine
opthalmic beta blockers
timolol and betaxolol
-prost drug class
prostaglandin analogs for glaucoma
-afil drug class
PDE-5 inhibitors for ED
PDE-5 inhibitors drug interaction
NGL -- both cause severe hypotension
1st gen antihistamine example
Diphenhydramine (Benadryl)
cause drowsiness
2nd gen antihistamine
cetirizine, fexofenadine, levocetirizine, loratadine
-erol drug class
beta agonists for astham/COPD
short acting beta agonists
albuterol, levalbuterol
long acting beta agonists
Salmeterol
Formoterol
-tropium drug class
inhaled anticholingerics for COPD
-lukast drug class
leukotriene modifiers for asthma and allergies
-osin drug class
alpha 1 blockers