Glucagon Pharmacology
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These flashcards cover key concepts regarding Glucagon, including its classification, mechanism of action, uses, dosing guidelines, side effects, and precautions.
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10 Terms
Glucagon
A pancreatic hormone that stimulates the release of glycogen from the liver and promotes glycogenolysis.
Mechanism of Action
Stimulates glycogen release (gluconeogenesis) and smooth muscle relaxation, increasing blood glucose levels.
Indications for Glucagon
Used for hypoglycemia, beta blocker overdose, and esophageal foreign body.
Hypoglycemia
A condition where blood glucose levels are less than 4.0 mmol/L and the patient is unable to take oral glucose.
Contraindications for Glucagon
Hypersensitivity and pheochromocytoma.
Dosage for Adult Hypoglycemia
1 mg IM, IV, or SQ; may repeat in 20 minutes if required.
Pediatric Dosage for Hypoglycemia
0.5 mg IM, IV, or SQ for children under 20 kg.
Dosage for Beta Blocker Overdose (Adult)
2 – 5 mg IV.
Side Effects of Glucagon
Nausea/vomiting, rebound hyperglycemia, hypotension, tachycardia.
Precautions when administering Glucagon
Effective only if sufficient glycogen stores are available; use with caution in patients with cardiovascular or renal disease.
Note 
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