E. Coli

Enterotoxic E. Coli: Exotoxin

Induces secretion of sodium and chloride into lumen of GIT, water follows.

Enterotoxic E. Coli: Clinical Signs

Watery diarrhea, no fever. Typically infects neonates (2 days - 3 weeks). Older animals are less susceptible.

Enteroinvasive E. Coli

Enters via the respiratory system, GIT, or umbilicus. Invades the cell and multiples eventually rupturing out of the cell. Bacteria may spread in the blood, ban lead to polyserasitis and cortical abscesses in kidneys.

Enteroinvasive E. Coli: Clinical Signs

Bloody diarrhea, mucous, and fever

Enteroinvasive E. Coli: Susceptible Animals

Newborns that do not have good immunity from colostrum.

Enteropathogenic E. Coli

Attaches to the microvilli via intimin (a bacterial outer membrane). Harms the host by destroying microvilli. Causes loss of digestiveenzymes, maldigestion, malabsorption, and diarrhea. Mainly attacks immunocompromised hosts.

Enterophathogenic E. Coli: Clinical Signs

Watery, chromic diarrhea, dilated fluid filled intestine, some inflammation, fever.

Enterohemorrhagic E. Coli

Food-borne disease in humans, resists the acid in stomach. Attaches via intimin. Moderately invasive entry. Produces verotoxin/shigatoxins

Enterohemorrhagic E. Coli: Clinical Signs

Bloody diarrhea, kidney failure, hemolytic uremic syndrome (HUS).