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Hemostasis
Right after injury - body stops bleeding by clotting.
Inflammation
1-5 days - red, swollen, warm, painful. Body fights infection.
Proliferation
5-21 days - new tissue grows (like scaffolding), skin starts to heal.
Maturation (Remodeling)
Weeks to a year - scar tissue forms, wound fully closes.
Partial-thickness
Skin surface (top layers).
Full-thickness
Goes deep into fat/muscle.
Surgical
Planned cut/incision during surgery.
Traumatic
Accidental injuries (e.g. cuts, abrasions).
Pressure injuries
Caused by prolonged pressure, usually over bony areas.
Diabetic ulcers
Caused by nerve damage + poor blood flow.
Venous ulcers
Poor return of blood from legs.
Arterial ulcers
Caused by blocked arteries and poor circulation.
Clean
No germs, no infection.
Clean-contaminated
Controlled entry into the respiratory, genital or urinary tract without major contamination.
Contaminated
Dirty wound or open injury.
Infected
Pus or signs of infection, or tissue death.
Serous
Clear, watery fluid.
Serosanguinous
Pinkish, watery blood mix.
Sanguineous
Red, watery bleeding.
Purulent
Yellow/green, thick, pus (infected).
Tophi
White, thick (urate crystals - gout).
Granulation
Bumpy, red/pink healthy healing tissue.
Hypergranulation
Too much granulation tissue.
Slough
Yellow/gray, soft stringy dead tissue.
Eschar/Necrotic
Thick black or brown dead tissue.
Epithelialization
Pink new skin growing over the wound.
Maceration
Water-logged, soft, white skin.
Erythema
Redness.
Induration
Hard around the wound.
Callous
Thickened skin from friction/pressure.
Undermining
Wound extends under the skin edges.
Tunneling
Wound forms a narrow passage into deeper tissues.
Moisture Management
Keep the wound moist, not wet. Moisture supports cell growth and healing.
Debridement
Removing Dead Tissue.
Autolytic
Body breaks down dead tissue itself.
Mechanical
Physical removal using Wet-to-dry dressings, or irrigation.
Enzymatic
Uses topical enzymes to dissolve necrotic tissue.
Biological
Medical maggots or leeches, Eats only dead tissue.
Irrigation
Use normal saline to cleanse the wound and remove debris, avoid cytotoxic solutions like hydrogen peroxide unless specifically indicated.
Odor Control
Use charcoal or silver dressings (e.g., Actisorb Silver) if the wound has a strong smell.
Negative Pressure Wound Therapy (NPWT)
Suction removes fluid, pulls edges together, and stimulates healing.
Offloading and Pressure Relief
Float heels, turn q2h, use air mattresses or foam cushions.
Factors Influencing Wound Healing
Patient-Related: Age, nutrition, hydration, comorbidities (e.g., diabetes), smoking status, and mobility.
T.I.M.E. Framework
The T.I.M.E. framework helps you assess and manage wounds by focusing on four key components that must be optimized for healing.
T.I.M.E. Framework - T
Tissue (Non-viable or Deficient?) Goal: Remove dead (non-viable) tissue to promote healing.
T.I.M.E. Framework - I
Infection or Inflammation Goal: Reduce infection and control inflammation.
T.I.M.E. Framework - M
Moisture Balance Goal: Keep the wound moist but not too wet.
T.I.M.E. Framework - E
Edge of Wound (Advancing or Not?) Goal: Get the wound edges to migrate and close.
Phases of Wound Healing - Hemostasis
Occurs immediately after injury, Platelets form clots and stop bleeding, Blood vessels constrict briefly.
Phases of Wound Healing - Inflammation
1-5 days, Redness, swelling, pain, warmth, White blood cells fight bacteria and remove debris.
Phases of Wound Healing - Proliferation
5-21 days, Granulation tissue forms, Collagen builds new tissue, New blood vessels form (angiogenesis), Epithelial cells resurface the wound.
Phases of Wound Healing - Maturation/Remodeling
Weeks-months, Collagen is reorganized, Scar strengthens over time, May take up to 1 year.
Partial-Thickness Wounds
Involves epidermis and part of dermis, Usually heals by regeneration. EX: Stage 2 pressure injury.
Full-Thickness Wounds
Involves epidermis, dermis, subcutaneous tissue, and possibly muscle/bone, Heals by scar formation, EX: Surgical wound with deep tissue exposure.
Wound Debridement - Autolytic
Uses body's own enzymes/moisture.
Wound Debridement - Surgical
Cutting out dead tissue with scissors or scalpel, Requires trained professional.
Wound Debridement - Mechanical
Physical removal (e.g., wet-to-dry dressings, wound irrigation).
Factors Delaying Wound Healing - Poor perfusion
Less oxygen and nutrients to tissue.
Factors Delaying Wound Healing - Infection
Prolongs inflammation and tissue damage.
Factors Delaying Wound Healing - Diabetes
Impairs circulation and immune response.
Factors Delaying Wound Healing - Smoking
Reduces oxygen and delays cell repair.
Infusion Therapy
The administration of fluids, medications, blood products, or nutrients into the bloodstream or body tissues.
Hypodermoclysis (HDC)
A method of administering fluids subcutaneously.
Hypodermoclysis
Subcutaneous infusion of fluids.
Indications for Hypodermoclysis
Mild to moderate dehydration, especially in older adults, palliative care clients, patients with poor IV access, and clients in long-term care.
Contraindications of HDC
Severe dehydration or shock, need for rapid fluid replacement, bleeding disorders, local skin infections.
Advantages of HDC
Less invasive and painful than IVs, fewer complications, easy to initiate and manage, can be used at home or in LTC, safer for frail or elderly clients.
Disadvantages of HDC
Slower absorption than IV, not suitable for emergency or rapid fluid replacement, volume limits per site (usually 1-2 mL/min; max ~1.5-3 L/day depending on patient and site).
Common Sites for Hypodermoclysis
Abdomen (most common and comfortable), thighs (good for mobility-limited clients), upper arms (alternate site), upper back (used when others are not suitable).
Fluids Commonly Used
Normal saline (0.9%), Half Normal Saline (0.45%), D5W (Dextrose 5% in water).
Administration Tips for HDC
Use butterfly needle or small gauge (24-27G), warm fluid before starting, elevate bag above insertion site, use infusion pump if ordered or gravity with flow control.
Additives in HDC
Hyaluronidase (sometimes used): helps spread fluid into tissue faster (not always available).
Monitoring in HDC
Local edema, redness, pain, leaking, infection, absorption, patient discomfort.
When Is HDC Most Commonly Used?
Palliative care, elderly clients in LTC, dehydrated clients with poor veins, clients refusing IVs.
Documentation for HDC
Site used, solution type and volume, rate of infusion, patient's tolerance, site condition and skin integrity.
Equipment Needed for HDC
Subcutaneous infusion set (e.g., butterfly needle), appropriate fluid bag, tubing and connectors, alcohol swabs, transparent dressing, infusion pump or gravity setup.
Procedure for HDC
Verify physician's order, perform hand hygiene and don gloves, select and prepare the infusion site, clean site with alcohol swab for 30 secs, let dry, insert the needle at a 45-degree angle, secure the needle with a transparent dressing, connect tubing and start infusion at prescribed rate, monitor the site and patient response.
Infusion Rates
Typical rate: 30-50 mL/hr; Maximum volume: 1,000-1,500 mL per 24 hrs.
Interventions for HDC
If complications arise, discontinue infusion and notify HCP, rotate sites if needed, ensure proper technique and equipment usage.
Common Sites for Subcutaneous Infusion
Abdomen (most common and well tolerated), lateral thighs, upper arms (posterior area), upper back (especially in frail or bed bound clients).
Typical Rate of Infusion
30-50 mL/hr.
Maximum Volume for Infusion
1,000-1,500 mL per 24 hrs.
Patient Monitoring in HDC
Monitor for local edema, redness, pain, leaking, infection, absorption, and patient discomfort.
Comfort in HDC
Hypodermoclysis is ideal for hydration when comfort, ease, and safety are more important than speed.
Steps for initiating hypodermoclysis infusion
1. Gather supplies: IV fluid bag (e.g., NS), butterfly needle (24-27G), tubing, dressing; 2. Wash hands and don gloves; 3. Select site (abdomen, thigh, arm, back); 4. Clean site with antiseptic using aseptic technique; 5. Insert butterfly needle into subcutaneous tissue at 45-90° angle; 6. Secure needle and connect tubing; 7. Start infusion (via gravity or pump); 8. Label site and monitor for swelling, redness, or leakage; 9. Document site, solution, rate, patient tolerance.
Complications of hypodermoclysis
Local swelling or edema, redness or irritation, leakage of fluid at insertion site, pain or discomfort, infection.
IV Therapy
The administration of fluids, medications, or nutrients directly into a vein.
Uses of IV Therapy
Hydration, medication delivery, blood transfusions, electrolyte balance, emergency interventions.
Isotonic IV Solutions
Normal Saline (0.9%), Lactated Ringers; used for fluid replacement; same tonicity as blood.
Hypotonic IV Solutions
0.45% NS, D5W; used for dehydration in cells (pulls fluid into cells).
Hypertonic IV Solutions
D5NS, D10W; used for pulling fluid out of cells - used with caution.
Phlebitis
Red, warm, tender vein; if occurs, stop infusion, remove IV, apply warm compress.
Infiltration
Cool, swollen, pale site; if occurs, stop infusion, elevate, apply warm compress.
Fluid overload
Symptoms include crackles, SOB, edema; if occurs, slow or stop infusion, notify team.
IV Flow Rates
Gravity drip: count drops per minute (gtt/min); Pump infusion: set in mL/hour.
Indwelling catheter (Foley)
A soft tube placed through the urethra into the bladder, held in place by a balloon; used for urinary retention, during/after surgery, strict I&O monitoring, skin breakdown from incontinence, end-of-life care.
Advantages of Foley catheter
Continuous drainage, accurate output monitoring, can stay in place for days/weeks.
Disadvantages of Foley catheter
Higher risk of CAUTI, can cause urethral trauma, reduced mobility.
Nursing Care for Foley catheter
Secure catheter, keep bag below bladder, empty q8h or when ¾ full, clean perineum and tubing daily, assess for infection.
Common Urinary Catheter Sizes
Adult Female: 14-16 Fr; Adult Male: 16-18 Fr.