Chromosomes & DNA
Structures in the cell nucleus carrying genetic instructions. Humans have 23 pairs.
Genes
Specific DNA segments coding for traits. Different forms are called alleles (e.g., eye color).
Variation
Alleles can cause different traits (e.g., blue vs. brown eyes).
Double Helix
DNA is structured as two coiled strands.
Base Pairs
Adenine (A) pairs with Thymine (T), and Cytosine (C) pairs with Guanine (G).
Punnett Squares
Predict inheritance probabilities.
Genotype
Genetic makeup (e.g., AA, Aa).
Phenotype
Observable traits (e.g., eye color).
Recessive Allele
Expressed only with two copies (e.g., aa).
Dominant Allele
Masks recessive traits (e.g., A in Aa).
Mutations
Changes in DNA, which can be harmless, beneficial, or harmful.
Inheritance
Mutations in germ cells can be passed to offspring.
Down's Syndrome
Cause: Extra copy of chromosome 21 (trisomy 21).
Effect: Developmental and physical challenges.
Anorexia
Extreme calorie restriction.
Obesity
Excessive weight gain with health implications.
GDA
General daily nutrient recommendations.
RDA
Specific daily nutrient needs.
Food Labelling
Includes traffic light labels, use-by dates.
Insulin
Regulates blood glucose levels.
Type 1 Diabetes
Autoimmune destruction of insulin cells.
Type 2 Diabetes
Insulin resistance and reduced production.
Alpha Radiation
Low penetration, high ionising.
Beta Radiation
Moderate penetration and ionising.
Gamma Radiation
High penetration, low ionising.
External Radiotherapy
Uses X-rays from outside the body.
Internal Radiotherapy
Radioactive sources placed inside or near the tumor.
Criteria for Selection of Radioisotopes
Factors: Half-life, type of radiation, medical purpose.
Chemotherapy
Uses chemicals to kill or inhibit cancer cells. Often combined with radiotherapy.
Medical Imaging
X-rays: Bones and some organs.
Ultrasound: Soft tissues, pregnancy monitoring.
MRI: Detailed images of soft tissues
Ultrasound
Pregnancy monitoring, diagnosing conditions.
X-rays
Two-dimensional images.
CAT Scans
3D imaging, combines multiple X-ray images.
Antigens
Foreign molecules recognized by the immune system.