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Canine TPR
100-102.2, 60-160, 16-32
Feline TPR
100-102.2. 140-220, 20-42
Equine TPR
99-101.5, 28-44, 6-16
Bovine TPR
100.4-103.1, 40-80, 10-30
Ovine/Caprine TPR
102-104, 70-90, 12-30
Porcine TPR
101.5-103.5, 70-120, 10-40
True or False: All drugs are potential poisons
True
What is the therapeutic Range
The safe zone, the amount of drug to achieve desired effect
True or False: The therapeutic Range is the amount that will cause toxicity
False
True or False: More is better in terms of drugs
False
What are the six R's
Right Patient
Right Drug
Right Dose
Right Route
Right Time
Right Documentation
What is the goal of drug therapy
to deliver the desired concentration of drug to achieve desired effect with little to no signs of toxicity
What are three factors to consider when using drug therapy
drug dose, dose interval, route
Routes
Parenteral and Non-Parenteral
Parenteral
other than GI
Non-Parenteral
GI
What are some drug factors
diff effects when given through diff routes, some drugs are insoluble in water, some are destroyed by stomach acids
What does it mean when a drug is insoluble in water
it can be given IM but not IV
What are local routes of drug admin
inhalation, topical, rectal, vaginal, transdermal
What are some non-parenteral routes of drug admin
oral - most convenient, less adverse reactions, does not have to be sterile
What kind of vials are there for injectable drugs
Multi-Dose Vials, Single Dose Vials, and Ampules
Bolus
Injecting a concentrated amount of drug in minimal amount of fluid
Intermittent
diluting drug in small volumes of fluid; give over 30-60 mins, through IV catheter
Infusion
Give large volumes of fluids continuously over long period of time
Solution
a clear liquid, typically a solute mixed with a solvent
Suspenstion
contains drug particles that can be seen (cloudy appearance)
Emulsion
mix of 2 liquids that don't mix
Repository Form
slow-release meds given over a certain amount of time
Volatilized Form
liquid that is vaporized for inhalation (for anesthetic)
Nebulized Form
liquid that is turned into a fine mist to be inhaled
Dose
amount administered at one time to reach the desired effect
Loading Dose
initial does will be higher than normal dose for maintenance (to reach therapeutic dose)
Maintenance Dose
amount of drug given to maintain blood levels
Total Daily Dose
amount of drug given w/in 24 hrs
Dosage
amount of drug given per unit of body weight
Dosage Interval
frequency of administration
What is the difference between state and federal laws
state laws are more restrictive and the veterinarian must follow it
FDA regulations
dispensing meds, set standards for what is on the drug label, set species, route, dosage, length of time, med can be used, controls prescription drugs
USDA
vaccines and biologics
Durham-Humphrey Amendment of 1951
Restricts availability of certain drugs due to (potential) toxicity. (Rx drugs)
Legend Drugs
prescription drugs
Warning label
federal law restricts this drug to be used by or upon the order of a licensed veterinarian
AVMA Rx drugs
rx drug must be dispensed by the written order of our vets w/in their course of practice and w/ a valid VCPR
OTC
over the counter Drugs
extra label or off label
used meds on species it's not approved for or a condition it's not meant for
Found in USP (drug standards and package inserts)
ensures pills meet quality, also supplies info about the meds on the box and on the USP web
USP
US Pharmacopeia
What is the potential for controlled drugs?
Potential for human abuse/misuse
Which agency regulates controlled drugs?
DEA
What are the schedules for controlled drugs?
Schedule I-V (1-5), higher the number, the less controlled it is
Where are controlled drugs kept?
In a locked room
Who must have a current DEA license to handle controlled drugs?
Veterinarian (Vet)
How are controlled drugs stored?
In a locked drug cabinet
For how long must records of controlled drugs be kept?
2 years
What must be kept accurately for controlled drugs?
Drug logbooks
what are benefits of dispensing
stock is in house, more convenient
What is included on the written Rx
Vets name, address, phone number
Clients name and address
Pents name and species
Name of drug, strength, qty disp.
Instructions for use
Date of Rx number of refills, exp. Date
Vet's signature
Auxiliary labels
Who regulates disposal of controlled drugs
DEA
Dose
total amount given at one time
Dosage
amount of drug given per unit of body weight
Mites
live on host continuously and can infect other animals through contact, life cycles: burrow or superficial mites
Sarcoptes scabiei
scabies

Demodex spp.
red mange mite

Notoedres cati
Feline scabies

Otodectes cynotis
ear mite

Supplies for a skin scrape
scalpel blade, mineral oil, microscope slide
what should be done to the scalpel blade before the skin scrape
dull the scalpel with a tongue depressor
After dulling the blade, what is next
place a dot of mineral oil on the slide and dip the blade in the mineral oil
After dipping the blade, what next
scrape the skin until you see blood
After scraping the skin, what next
dip the blade back onto the slide with mineral oil and get all of the debris on the blade onto the slide
What should the skin scrape be viewed under
4x and 10x
What is the first step for an ear mite smear
prepare slide w/ mineral oil
How should an ear swab sample be obtained
with a restrainer, pull up the pinna of the ear and swab part of the outer ear containing debris
What is the second step for an ear mite smear
roll the swab onto the slide in the oil
What is the third step for an ear mite smear
break applicator stick and scrape off any debris
What view should an ear mite smear be viewed under
4x and 10x
What does yeast look like
bowling pin/boot print
What is the species of yeast
Malassezia
What is the first step for a cytology
swab affected area (ear/skin)
What is the second step for a cytology
roll the swab onto the slide
What is the third step for a cytology
heat fix
What is the fourth step for a cytology
Stain (light blue, red, then methylene blue)
What is few yeast considered
0-2 per every other field
What is moderate yeast considered
2-3 per field
What is many yeast considered
5+
what is /hpf
per high powerfield
What should a cytology be viewed under
40x and 100x
How should a touch prep be prepared for oozy skin
touch slide directly to it, stain, heat fix, and examine
How should a nail bed swab be prepared
run a Q-tip around the nail bed, stain, heat fix, examine
How should a tape prep be prepared
clear scotch tape applied directly to the affected area several times, skip fixative but still stain
Rods
pinkish-purple, note rod chains
Cocci
blue, note clusters
What is the purpose of bathing an animal
to help them recover from illness, less likely to develop dermatitis, prevention/tx of skin probs, good client relations
What kind of grooming supplies are needed
ear flushes, brushes, gloves, eye lube, etc
What should you give a cat when bathing them
something to hold onto
What are tar-sulfur shampoos used for?
oily, flaky, seborrheic conditions
What are Benzoyl peroxides used for
bacterial skin infections
What are sulfur-salicylics used for
dry, flaky, seborrheic conditions
Colloidal
for pruritis
When and what are insecticidals used for
under veterinary guide and for fleas, ticks, and mites