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Over 480,000
Smoking causes how many U.S. deaths yearly?
1963 (~40% adults smoked)
When did U.S. Cigarette use Peak?
~10 seconds
How quickly does nicotine reach the brain?
Nicotinic acetylcholine receptors
Nicotine’s Key Receptor target?
Irritability, anxiety, restlessness, insomnia, increased appetite
Nicotine withdrawal symptoms
Metabolizes nicotine
CYP2A6 enzyme function?
Used for self-medication; increases relapse risk
Why is smoking linked to mental illness?
More anxiety/depression, weight gain concerns, hormonal cycle effects
Why is quitting harder for women?
~26.7%
E-Cig use prevalence among high school seniors?