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Signs
-objective findings of neuro dysfunction
Symptoms
-subjective reports
Posiitve symptoms
-release of abnormal behaviors
-ex: babinski sign
Negative symptoms
-loss of normal behaviors
-ex: paresis
Primary effects
-motor
-sensory/perceptual
-cognitive/behavioral
Secondary effects
-motor control problems
-don't result from CNS lesion directly
-are a result of a problem
Damage to motor cortex neurons or descending corticospinal pathways results in
-UMN syndrome
What happens initially after injury to motor cortex?
-spinal shock-->flaccidity
Strength
-ability to generate force
-results from musculoskeletal properties and neural activation
Neural aspects of force production
-number of motor units recruited
-type of units recruited
-discharge frequency
Paralysis (plegia)
-total loss of muscle activity
-inability to recruit high-threshold motor units
-component of UMN syndrome
paresis
-mild or partial loss of muscle activity
Muscle tone
-characterized by muscle's resistance to passive stretch
hypertonicity
-increased muscle tone
-spasticity
-rigidity
hypotonicity
-low muscle tone
spasticity
-A motor disorder characterized by velocity-dependent increased muscle tone, exaggerated tendon jerks, and clonus; the result of an upper motor neuron lesion.
-describes many abnormal behaviors
sign of spasticity
-velocity-dependent increase in resistance to passive stretch
spasticity neural mechanism
-abnormality in the segmental stretch reflex
-denervation hypersensitivity
-collateral sprouting
Individuation
-ability to selectively activate a muscle, allowing isolated joint motion
What happens when we lose individuation
-activation of one muscle is abnormally coupled with other related muscles
-decreased function
Coactivation
-simultaneous activation of muscles during functional mvmts
-present in neuro intact people just learning a skill
-also present in neuropathology
Cerebellar pathology may result in
-hypotonia
-ataxia or intention tremor
-dyssynergia (decomposition of mvmt)
-dysdiadochokinesia (inability to perform rapid alternating mvmts)
-dysarthria (deficits in articulating words)
-difficutly regulating cognition, emotion, and autonomic functions
Cerebellar discoordination manifestations
-dysmetria
-dysdiadochokinesia
-hypometria
-hypermetria
dysmetria
-inability to sustain regular rhythmic mvmts
hypometria
-underestimation of the required force or range of movement needed for specific task
-undershoot
hypermetria
-overestimation of req force or range of movement needed for specific task
-overshoot
intention tremor
-A tremor that occurs during performance of a voluntary motor act. Characteristic of cerebellar pathology.