Looks like no one added any tags here yet for you.
Innate immune system
Fast reaction to general antigens
Does not improve if re exposed
Activates adaptive
Adaptive immune system
Slower response to specficic antigens
Memory
What cells are in the innate immune system
Macrophages
Neutrophils
Dendritic cells
Eosinophils
Mast cells/basophils
Natural killer cells
Macrophages
—>First responders
—>activated by complement system and PAMPs via TLRs
—>Phagocytosis, APCs, secrete cytokines,
—>Produce lipid mediators
Neutrophils
—>First cells that arrive in mass numbers
—>Activated by TLRs, complement system, TNF-alpha, interleukins
—>Pahgocytosis, secrete cytokines
Dendritic cels
Activated by TLRs
Phagocytosis, APCs, secrete cytokines
Eosinophils
—>Activated by IL5, Ige
—>Kill parasites, secrete cytokines
Mas cells/basophils
—>Activated by C3a, C5a, IgE
—>Secrete histamine and cytokines
Natural killer cells
—>Type of innate lymphoid cell
—>Recognize aletered self
—>Apoptosis
Adaptive immune system componenets
B cells make antibodies
T cells= cytotoxic, helper, regulatory
Immunoglobulins
2 light and 2 heavy chains
Varaible region
Constant region
Class switching (switch from M & D)
T cells
MHC 1 presents to CD8+ (cytotoxic) T cells
MHC2 presents to CD4+ (helper) T cells