PHARM101A Hypnotics, Sedative, and Tranquilizers

Sedatives

induces sleep but more on motor/physical effects

Tranquilizers

induces sleep but more on mental effects

• barbital

• phenobarbital

• secobarbital

• amobarbital

Barbiturates

Chloral hydrate

good hypnotic, but a poor anesthetic

Diazepam

Benzodiazepine that is also an anticonvulsant

Diazepam

Benzodiazepine combined with ketamine HCl will lessen cardiovascular and respiratory effects

Chlordiazepoxide

Benzodiazepine that causes icterus (jaundice)

• diazepam

• midazolam

• zolazepam

• chlordiazepoxide

Benzodiazepines

• acepromazine

• chlorpromazine

• promazine

• triflupromazine

• ethylisobutrazine

Phenothiazine

Acepromazine

Phenothiazine that causes priapism (penile prolapse) in horses

Chlorpromazine

Phenothiazine used as an atiemetic and anti arrhythmia

Epinephrine

Contraindicates chlorpromazine

Promazine

Phenothiazine rarely used in equine

Promazine

Phenothiazine that causes little excitation in horses followed by depression

Triflupromazine

Phenothiazine that affects the erythrocytes/RBC and causes anemia in sheep

Ethylisobutrazine

Phenothiazine commonly used in canine when grooming (chemical restraint)

Triflupromazine

Phenothiazine that is generally used across all animals

Ethylisobutrazine

Phenothiazine that is a hypnotic sedative

Ethylisobutrazine

Phenothiazine that is used to decrease self mutilation, especially related to dermatoses (pruritus, dog biting itself)

Chlorprothixene

Thioxanthene used as a preanesthetic, hypnotic, sedative, antiemetic and atihistamine

acepromazine and chlorpromazine

Phenothiazines used as a preanesthetic, hypnotic, sedative, and traquilizer

Chlorprothixene

Thioxanthene when used a as a preanesthetic, produces decreased body temperature

• haloperidol

• droperidol

• azaperone

• lenterone

Butyrophenones

Haloperidol

Butyrophenone used as preanesthetic, hypnotic, sedative, antiemetic

Epinephrine

halperidol as a preanesthetic can be contraindicated by

Droperidol

Butyrophenone used as hypnotic, sedative, tranquilizer

Azaperone

Butyrophenone that was used as a sedative and tranquilizer pre pandemic, in misbehaving piglets during farrowing and gilts that refuse to farrow

Azaperone

Butyrophenone later replaced by alcohol drinks because anesthetic drugs are no longer used in livestock pigs

Lenterone

Butyrophenone used as a hypnotic, sedative, tranquilizer, antiemetic, and anxiolytic drug

Rauwolfia

reserpine (both AND and CNS drug)