The Plasma Membrane: Transmembrane Proteins

The intracellular domain of transmembrane proteins is hydrophilic.

True

Membrane-spanning channels formed by alpha helices can be formed from varying number of alpha helices.

True

The extracellular domain of transmembrane proteins is hydrophobic.

False

The transmembrane domain of a transmembrane protein interacts with:

Both hydrophobic and hydrophilic regions of the lipid bilayer

The extracellular domain of a transmembrane protein would typically have a different function than the intracellular domain.

True

Transmembrane domains can be formed by a single alpha helix, but not by multiple alpha helices.

False

Within transmembrane proteins, the intracellular domain is usually \[blank\] the extracellular domain.

Chemically different than

What would not be able to form an aqueous channel that spans the lipid bilayer?

A single alpha helix

For a transmembrane domain that consists of a single alpha helix, the hydrophilic residues within the alpha helix are located around the exterior of the helix.

False