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heredity
the transmission of traits from one generation to the next
variation
differences between members of the same species
genetics
the study of both heredity and inherited variations
locus
a gene’s specific location along the length of a chromosome
asexual reproduction
reproduction where a single individual is the sole parent and passes copies of all its genes to its offspring without the fusion of gametes
clone
an individual or group of individuals that are genetically identical to the parent
s-xual reproduction
reproduction where two parents give rise to offspring that have unique combinations of genes inherited from the two parents
life cycle
the generation-to-generation sequence of stages in the reproductive history of an organism, from conception to production of its own offspring
karyotype
a display of the chromosome pairs in a cell arranged by shape and size
homologous chromosomes
the two chromosomes of a pair that have the same length, centromere position, and staining pattern
s-x chromosmes
X and Y chromosomes with a role in s-x determination
autosomes
every other chromosome in the cell other than s-x chromosomes
diploid cell
any cell with two chromosome sets
haploid cells
cells that contain a single set of chromosomes
fertilization
the union of gametes, culminating in fusion of their nuclei
zygote
the resulting fertilized egg from fertilization
meiosis
the type of cell division that reduces the number of sets of chromosomes from two to one in gametes
alternation of generations
a second type of life cycle exhibited by plants and algae where a diploid and haploid organism arise
meiosis I
the first stage of meiosis where homologous chromosomes are separated
meiosis II
the second stage of meiosis where sister chromatids are separated
synaptonemal complex
a zipper-like structure that connects a chromosome to its homolog during prophase I of meiosis
synapsis
the physical connection of a replicated chromosome to its homolog
chiasma
the location where crossing over occurs and where sister chromatid cohesion occurs
character
a heritable feature that varies among individuals
trait
each variant for a character
true-breeding
organisms that produce offspring with only the same variety as the parent through self-pollination
hybridization
the mating of two true-breeding varieties
P generation
the true-breeding parental generation in hybridization
F1 generation
the first filial generation, the hybrid offspring of the parental generation
F2 generation
the second filial generation, either from hybridization or self-pollination of first filial generation
alleles
alternative versions of a gene
dominant allele
the allele that determines an organism’s appearance
recessive allele
the allele that has no noticeable effect on an organism’s appearance
law of segregation
the idea that two alleles for a heritable character segregate during gamete formation and end up in different gametes
Punnett square
a diagrammatic device for predicting the allele composition of all offspring resulting from a cross between individuals for known genetic makeup
homozygote
an organism that has a pair of identical alleles for a gene encoding a character
homozygous
the property of having two identical alleles for a character
heterozygote
an organism that has two different alleles for a gene
heterozygous
the property of having two different alleles for a character
phenotype
an organism’s appearance or observable traits
genotype
an organism’s genetic makeup
testcross
the breeding of an organism of unknown genotype with a recessive homozygote
monohybrids
organisms that are heterozygous for one particular character being followed
monohybrid cross
a cross between two monohybrid heterozygotes
dihybrids
organisms heterozygous for two characters being followed
dihybrid cross
a cross between F1 dihybrids
law of independent assortment
the idea that two or more genes separate independently during gamete fusion
multiplication rule
the rule that determines the probability of one event and another occurring by multiplying the two probabilities of each event together
addition rule
the rule that determines the probability of one event or another occurring by adding their individual probabilities
complete dominance
situations where the phenotypes of heterozygote and the dominant homozygote are indistinguishable
incomplete dominance
the phenomenon where, in some genes, neither allele is completely dominant
codominance
the variation of dominance where two alleles affect the phenotype in separate, distinguishable ways
Tay-Sachs disease
an inherited disorder in humans where brain cells cannot metabolize certain lipids because a crucial enzyme does not work properly
pleiotropy
the property of genes to have multiple phenotypic effects
epistasis
where the phenotypic expression of a gene at one locus alters that of a gene at a second locus
quantitative characters
characters that are not just one of two discrete characters, but vary in a population in gradations along a continuum
polygenic inheritence
an additive effect of two or more genes on a single phenotypic character
phenotypic plasticity
the ability of an individual genotype to produce different phenotypes under different environmental conditions
multifactorial
when many factors, both genetic and environmental collectively influence phenotype
pedigree
a family tree describing the traits of parents and children across the generations
carriers
phenotypically normal heterozygotes that may transmit a recessive disorder allele to their offspring
cystic fibrosis
a common lethal genetic disease in the United States where chloride transport channels are defective
Huntington’s disease
a degenerative disease of the nervous system