glycogen degradation

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17 Terms

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Glycogenin

Protein that is linked to glycogen

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Alpha-1,4-glycosidic bonds, alpha-1,6-glycosidic bonds, 8-15

The structure of glucose: glucosyl residues are linked by … and branches … that occur every … glucosyl residues

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Liver

Where glycogen synthesis and degradation occurs to maintain the blood glucose concentration for the whole body even during the nighttime to fuel the brain

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In the muscle itself

Where glycogen breakdown occurs to meet the energy needs of the muscles to create the ATP they require

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Glycogen phosphorylase, nonreducing ends

Enzyme that degrades glycogen … , it starts the degradation from the …

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Glucose-1-phosphate

Phosphorylase catalyzes phosphorlysis reaction that breaks of a … from the glycogen molecule

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Glucose-6-phosphate, phosphoglucomutase

For glucose-1-phosphate to enter glycolysis it first must change to … within the liver only by …

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Alpha-1,4-glycosidic bonds

Glycogen phosphorylase cannot cleave near branch points only …

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Transferase

For phosphorylase to access a glucose that is inaccessible use to a oligosaccharide … transfers this oligosaccharide to a nearby chain

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Debranching enzyme

Enzyme that is used to cleave alpha-1,6-glycosidic bonds to release free glucose

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Glucose-6-phosphatase

Enzyme that generates free glucose from glucose-6-phosphate only in the liver

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Glycogen phosphorylase

Key regulatory enzyme for glycogen degradation

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Epinephrine and glucagon

The 2 hormones that cause breakdown of glycogen

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Muscle activity

What cause release of epinephrine

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Muscle

Organ that is more responsive to stimulation of glycogen breakdown by epinephrine to fully go through glycolysis and create lactate

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Liver

Organ that is more responsive to stimulation of glycogen breakdown by glucagon to create glucose

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The depletion of glycogen reserves

The onset of fatigue coincides with