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These flashcards cover key concepts related to the anatomy and physiology of the heart, cardiovascular system functions, electrical conduction, and clinical relevance.
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Cardiovascular system
System that includes the heart, blood, and blood vessels.
Heart rate
The number of beats per minute of the heart.
Stroke volume
The amount of blood pumped by the left ventricle in one contraction.
Cardiac output
The volume of blood the heart pumps per minute; calculated as heart rate multiplied by stroke volume.
Atrioventricular (AV) valves
Valves located between the atria and ventricles, including the tricuspid and mitral valves.
Semilunar valves
Valves located between the ventricles and arteries, including the aortic and pulmonary valves.
Fossa ovalis
An oval-shaped scar on the interatrial septum of the heart, a remnant of the foramen ovale.
Foramen ovale
An opening in the fetal heart that allows blood to bypass the lungs.
Pericardium
The fibrous sac that encloses the heart.
Myocardium
The muscular layer of the heart responsible for contraction.
Endocardium
The innermost layer of the heart lining the chambers and valves.
Coronary arteries
Blood vessels that supply blood to the heart muscle.
Capillaries
Small blood vessels where exchange of substances occurs.
Pacemaker cells
Cells in the heart that initiate and regulate the heartbeat.
Sinoatrial (SA) node
The primary pacemaker of the heart located in the right atrium.
Atrioventricular (AV) node
A cluster of cells that serves as an electrical relay station between the atria and ventricles.
Electrical conduction system
A network of pacemaker and conducting cells that coordinate heart contractions.
Cardiac cycle
The sequence of events in one heartbeat involving contraction (systole) and relaxation (diastole).
Atrial contraction
Phase when the atria push blood into the ventricles.
Ventricular contraction
Phase when the ventricles eject blood into the arteries.
Cardiac tamponade
Restriction of heart function due to fluid accumulation in the pericardial cavity.
Coronary circulation
The flow of blood to and from the tissues of the heart.
Coronary artery disease (CAD)
A condition characterized by the narrowing of coronary arteries due to plaque.
Myocardial infarction (MI)
A heart attack caused by insufficient blood flow to the heart muscle.
Angina pectoris
Chest pain due to reduced blood flow to the heart muscle.
Ejection fraction
The percentage of end-diastolic volume that is ejected from the heart during contraction.
Preload
The degree of stretch of the heart muscle prior to contraction.
Afterload
The pressure against which the heart must work to eject blood.
Frank–Starling principle
The relationship between preload and stroke volume.
Bradycardia
Abnormally slow heart rate.
Tachycardia
Abnormally fast heart rate.
Ectopic pacemaker
An abnormal pacemaker that generates an action potential outside of the SA node.
Electrocardiogram (ECG or EKG)
A test to detect electrical activity of the heart.
P wave
The wave on an ECG representing atrial depolarization.
QRS complex
The wave on an ECG representing ventricular depolarization.
T wave
The wave on an ECG representing ventricular repolarization.
Pathophysiology
The study of disordered physiological processes.
Cardiac constrictions
Phenomena where the heart chambers momentarily lose their ability to pump effectively.
Calcium ions
Electrolytes crucial for heart contraction and signaling.
Refractory period
The period during which the heart muscle cannot be stimulated to contract again.
Desmosomes
Structures that provide adhesion between cardiac muscle cells.
Gap junctions
Protein channels that allow the passage of ions and electrical signals between cells.
Atrial systole
The contraction of the atria pushing blood into the ventricles.
Ventricular systole
The contraction of the ventricles pushing blood into the arteries.
Resting membrane potential
The electrical potential across the cell membrane when the cell is not firing.
Intercalated discs
Specialized connections between cardiac cells that facilitate electrical impulses.
Cardiomyocytes
Cardiac muscle cells responsible for the heart's contraction.
Tissue perfusion
The flow of blood to supply the tissues with nutrients and oxygen.
Ventricular diastole
The phase of the cardiac cycle when ventricles are relaxed and filling with blood.
Atrial diastole
The phase of the cardiac cycle when atria are relaxed.
Isovolumetric contraction
Phase in the cardiac cycle when the ventricles contract but no blood is ejected.
Flow of blood
The movement of blood through the circulatory system.
Aortic arch
The portion of the aorta that bends between the ascending and descending aorta.
Pulmonary circuit
The pathway of blood between the heart and lungs.
Systemic circuit
The pathway of blood between the heart and the rest of the body.
Mitral valve
The heart valve between the left atrium and left ventricle.
Tricuspid valve
The heart valve between the right atrium and right ventricle.
Pulmonary valve
The valve that opens into the pulmonary artery from the right ventricle.
Aortic valve
The valve that opens into the aorta from the left ventricle.
Ventricular filling
The process of blood entering the ventricles from the atria.
Diastolic pressure
Pressure in the arteries when the heart rests between beats.
Systolic pressure
Pressure in the arteries during heart contraction.
Cardiac reserve
The difference between resting and maximal cardiac outputs.
End-diastolic volume (EDV)
The volume of blood in the ventricles at the end of diastole.
End-systolic volume (ESV)
The volume of blood remaining in the ventricles after contraction.
Deoxygenated blood
Blood that is lacking in oxygen, returning to the heart from the body.
Oxygenated blood
Blood rich in oxygen, pumped from the heart to the body.
Pulmonary veins
Veins that return oxygenated blood from the lungs to the left atrium of the heart.
Superior vena cava
The large vein that carries deoxygenated blood from the upper body to the right atrium.
Inferior vena cava
The large vein that carries deoxygenated blood from the lower body to the right atrium.
Coronary sinus
A collection of veins that join to form a large vessel that collects blood from the heart muscle.
Chamber of the heart
One of the four separate compartments of the heart (atria and ventricles).
Compartmentalization of heart
The division of the heart into chambers to prevent mixing of oxygenated and deoxygenated blood.
Action potential
A momentary change in electrical potential on the surface of a cell.
Resting potential
The stable, negative charge of a cell when it is not generating an action potential.
Main arteries
Major blood vessels that carry oxygenated blood from the heart to the body.
Major veins
Large blood vessels that carry deoxygenated blood back to the heart.
Blood flow direction
The path blood takes as it traverses the circulatory system.
Valve function
To ensure unidirectional blood flow through the heart and vessels.
Valve types
Includes AV valves and semilunar valves.
Coronary circulation path
The route blood takes to supply the heart itself.
Plateau phase
In a cardiac action potential, the period during which the cell remains depolarized.
Calcium influx
The entrance of calcium ions into the cells, critical for muscle contraction.
Skeletal muscle vs cardiac muscle
Cardiac muscle has a longer action potential duration than skeletal muscle.
Domestic serenity
A term referring to the peaceful state of the heart when it is at rest.
Hemodynamic factors
Factors that influence blood flow properties.
Activity level
Physical exertion level which affects heart rate.
Electrical events
Changes in electrical potential that coordinate heartbeat.
Arterial blood flow
The movement of blood through arteries leading away from the heart.
Blood volume
Total amount of blood circulating in the body.
Electrophysiological characteristics
Properties of heart cells that enable them to generate electrical impulses.
Fluid mechanics
The study of how fluids move and behave.
Blood vessel structure
The composition of arteries, veins, and capillaries.
Venous return
The flow of blood back to the heart from the body.
Autonomic nervous system
The part of the nervous system that controls involuntary actions.
Sympathetic stimulation
Nervous signals that increase heart rate and strength of contractions.
Parasympathetic stimulation
Nervous signals that decrease heart rate.
Hemodynamics
The dynamics of blood flow.
Medulla oblongata
Part of the brain that controls autonomic functions, including heart rate.
Rheumatic fever
An inflammatory disease that can affect the heart.