Integrated Science II Exam 3 - Dr. Lewis

Which is NOT a component or a process associated with innate immunity?

A. Skin

B. Inflammation

C. Antibody production

E. Mucous membranes

C

A type of symbiotic relationship in which both symbionts are equally

benefited:

A. Commensalism

B. Parasitism

C. Mutualism

D. Opportunism

E. None of the above

C

A type of symbiotic relationship in which one organism is benefited and the other is unaffected:

A. Opportunism

B. Commensalism

C. Parasitism

D. Mutualism

E. None of the above

B

Which of the following is NOT a mechanical barrier?

A. Lacrimation

B. Lysozyme flow

C. Urination

D. Sneezing

E. Coughing

B

All blood cells in the body originate from this type of cells:

A. Erythrocyte

B. Eosinophlic stem cell

C. Mononuclear phagocytic cell

D. Pluripotent hematopoietic stem cell

E. Thrombocyte

D

The process of phagocytosis includes all of the following EXCEPT:

A. Chemotaxis

B. Recognition and attachment

C. Lysogeny

D. Engulfment

E. Digestion and Destruction

C

Which of the following is a phagocytic cell found in the human body?

A. Erythrocyte

B. B Cell

C. T Cell

D. Macrophage

E. Platelets

D

An enzyme that destroys white blood cells:

A. Hemolysin

B. Leukocidin

C. Coagulase

D. Stzeprokinase

E. None of the above

B

Which of the following microbes is the most virulent?

A. LD50 = 10A7

B. LD5O = 10A1

C. LD50 = 10A8

D. LD50 = 10A4

E. LD50 = 10A10

B

This individual observed a relationship between cowpox in dairy maids and smallpox:

A. Pasteur

B. Koch

C. Tyndill

D. Jenner

E. None of the above

D

This enzyme can destroy blood (fibrin) clots:

A. Coagulase

B. Streptokinase

C. Leukocidin

D. Hemolysin

E. None of the above

B

An individual is injected with antibodies to boost their immunity. What type of immunity is this?

A. Active

B. Passive

C. Both

D. Neither

B

In type I allergic reactions, antibodies are produced and bind to:

A. Mast cells

B. Neutrophils

C. Macrophages

D. Eosinophils

E. Monocytes

A

Which of the following is NOT a cardinal feature of inflammation?

A. Pain

B. Heat

C. Swelling

D. Immunodiffusion

E. Redness

D

This toxin causes massive diarrhea with characteristic rice-water stools:

A. Staphylococcal enterotoxin

B. E. Coli enterotoxin

C. Botulinum toxin

D. Vibrio enterotoxin

E. Strepto coccal erythrogenic toxin

D

A person with type AB blood has which type of antibody in their plasma?

A. Antibody A

B. Antibody B

C. Both

D. Neither

D

The specific cells that synthesize and secrete immunoglobulins:

A. T helper cells

B. Plasma cells

C. Cytotoxic T cells

D. Memory cells

E. Eosinophils

B

The antibodies found on the surface of B cells:

A. TCR

B. BCR

C. TLR

D. CD3 Complex

E. None of the above

B

Which cells differentiate into plasma cells?

A. T cells

B. Macrophages

C. Basophils

D. B cells

E. Eosinophils

D

Which of the following is a primary lymphoid organ?

A. Spleen

B. Peyer's patches

C. Tonsils

D. Lymph nodes

E. Thymus

E

All of the following are secondary lymphoid organs EXCEPT:

A. Spleen

B. Bone marrow

C. Lymph nodes

D. Tonsils

E. Peyer's patches

B

This immunoglobulin (pentamer) is the first one produced in response to

antigen stimulation:

A. IgM

B. IgD

C. IgE

D. IgA

E. IgG

A

This immunoglobulin can exist as a dimmer and is found in body secretions (eg. Saliva):

A. IgG

B. IgM

C. IgE

D. IgD

E. IgA

E

Inactivated toxins that are injected and used to induce antibody production:

A. Haptens

B. Toxigens

C. Hyperimmune globulin

D. Toxoids

E. Immune globulin

D

The only immunoglobulin that can cross the placenta and protect the newborn:

A. IgM

B. IgG

C. IgD

D. IgA

E. IgE

B

Which of the following immunoglobulins can bind to mast cells in allergic

responses:

A. IgG

B. IgD

C. IgM

D. IgA

E. IgE

E

Which of the following is an APC?

A. Plasma cells

B. T helper cells

C. NK cells

D. Macrophages

E. Cytotoxic T cells

D

This region of the antibody is responsible for binding antigen molecules:

A. Fe

B. Fab

C. Fap

D. Fd

E. CH1

B

Tc cells can accept antigen only when presented by:

A. MHC class I molecules

B. MHC class II molecules

C. MHC class III molecules

D. All of the above

E. None of the above

A

T H cells can accept antigen only when presented by:

A. MHC class I molecules

B. MHC class II molecules

C. MHC class III molecules

D. All of the above

E. None of the above

B

Which CD marker is found on the surface of T helper cells?

A. CD8

B. CD6

C. CD4

D. CD5

E. None of the above

C

Whooping Cough is prevented by the use of this vaccine:

A. MMR

B. IPV

C. DTaP

D. Hib

E. OPV

C

Which of the following cells can induce viral-infected cells to undergo

apoptosis?

A. Neutrophils

B. Bcells

C. NK cells

D. Basophils

E. Eosinophils

C

Administration of a vaccine is an example of:

A. Naturally acquired active immunity

B. Naturally acquired passive immunity

C. Artificially acquired active immunity

D. Artificially acquired passive immunity

E. None of the above

C

A fetus gets its antibodies by this type of immunity:

A. Naturally acquired active immunity

B. Artificially acquired active immunity

C. Naturally acquired passive immunity

D. Artificially acquired passive immunity

C

The attraction of leukocytes to the area of inflammation is referred to as:

A. Parasitism

B. Infection

C. Phototaxis

D. Chemotaxis

E. None of the above

D

Erythroblastosis fetalis is a condition of the newborn that results from a

hypersensitive reaction between a:

A. Rh+ mother and Rh- fetus

B. Rh+motherandRh+fetus

C. Rh- mother and Rh+ fetus

D. Rh- mother and Rh- fetus

C

An immunodeficiency characterized by a lack of T cells:

A. Agammaglobulinemia

B. DiGeorge syndrome

C. Chediak- Higashi disease

D. Graves' disease

E. Hemolytic Anemia

B

This autoimmune disease is characterized by autoantibodies binding to acetylcholine receptors:

A. Rheumatoid arthritis

B. Systemic lupus erythematosus

C. Graves' disease

D. Myasthenia Gravis

E. SCID

D

Transplantation of a baboon's heart into a human is this type of graft:

A. Autograft

B. Allograft

C. Isograft

D. Xenograft

D

Administration of antivenom for a snake bite is an example of this type of immunity:

A. Naturally acquired active immunity

B. Naturally acquired passive immunity

C. Artificially acquired active immunity

D. Artificially acquired passive immunity

D

Which class (es) of immunoglobulins are found on the B cell surface?

A. IgD

B. IgA

C. IgM (monomeric)

D. IgG

E. Both A and C

E

The discrete portions of an antigen where antibodies can bind to are

called:

A. Haptens

B. Antigenic determinants/ Epitopes

C. Monomers

D. Domains

B

A term synonymous with antibody is:

A. Antigen

B. Epitope

C. Determinant

D. Immunoglobulin

E. Immunogen

D

There are classes of antibody:

A. 1

B.3

C. 5

D. 7

E. None of the above

C

T cells develop and mature in the:

A. Bone marrow

B. Thyroid gland

C. Thymus

D. Peyer's patches

E. Nervous tissue

C

Name the category of antigenic determinant from the diagram:

A. Unideterminant, Univalent

B. Unideterminant, Multivalent

C. Multideterminant, Univalent

D. Multideterminant, Multivalent

B

Contact dermatitis is this type of hypersensitivity:

A. Type I

B. Type II

C. Type III

D. Type IV

D

A low molecular weight chemical that becomes an antigen when it binds to

a carrier:

A. Determinant

B. Hapten

C. Valence monomer

D. Opsonin

E. None of the above

B

Which vaccine is used to prevent polio?

A. IPV

B. HPV

C. MCV

D. PCV

E. RPV

A

Opportunists are:

A. Normal flora microorganisms

B. Commensals turned pathogenic

C. Can cause disease in debilitated patients

D. All of the above

E. None of the above

D

The type of hemolysis in which there is a complete breakdown of red blood cells?

A. Alpha hemolysis

B. Beta hemolysis

C. Gamma hemolysis Delta

D. hemolysis

B

The degree of pathogenicity of a microorganism is referred to as its:

A. Toxigenicity

B. Invasiveness

C. Virulence

D. Lethality

E. None of the above

C

Which of the following individuals proposed that only phagocytic cells were responsible for immunity?

A. Von Behring

B. Pasteur

C. Metchnikoff

D. Jenner

E. None of the above

C

Bacterial cell walls, capsules, flagella, etc. can be considered as:

A. PAMPS

B. PRRs

C. TLRs.

D. A and B

E. All of the above

D

This immunity has specific recognition and memory:

A. Innate

B. Adaptive

C. Both

D. Neither

B

Foreign substances that can induce the immune response:

A. Antibodies

B. Immunoglobulins

C. Antigens

D. A and B

E. None of the above

C

Injection of anti-venom into a patient for a poisonous snake bite is an example of:

A. Naturally acquired active immunity

B. Artificially acquired active immunity

C. Naturally acquired passive immunity

D. Artificially acquired passive immunity

D

A T cell which possesses a CD4 marker is known as a:

A. Tc cell

B. Td cell

C. Treg cell

D. Th cell

E. None of the above

D

Bacterial flagellar antigens are designated:

A. K antigen

B. 0 antigen

C. H antigen

D. V antigen

E. None of the above

C

Cytotoxic (blood transfusion incompatibility) hypersensitive reactions are:

A. Type I

B. Type II

C. Type III

D. Type IV

B

Immunoprophylaxis For Rh disease of the newborn involves:

A. Use of immunosuppressive drugs

B. Administration of Rh antibody (Rhogam) to remove and block Rh antigen

C. Administration or RH antigen to remove Rh antibody

D. Use of epitope-clearing enzymes

E. All of the above

B

This autoimmune inflammatory disease is characterized by chronic joint pain, a butterfly rash across the bridge of the nose and the presence on antinuclear antibodies (ANA)

A. Agammaglobulinemia

B. Rheumatoid arthritis

C. Systemic lupus erythematosus (SLE)

D. Graves' disease

E. Hemolytic anemia

C

Transplantation of tissue from one site of the body to another site on the body is this type of graft :

A. Autograft

B. Allograft

C. Isograft

D. Xenograft

A

All of the following are autoimmune diseases EXCEPT:

A. Graves'

B. Hashimoto's Thyroiditis

C. SCID

D. Rheumatoid arthritis

C

Which of the following cells of the innate immune system can recognize stress molecules on aberrant or viral-infected cells and attack and kill these target cells?

A. Macrophages

B. Natural killer cells

C. CD4 tells

D. Dendrite cells

E. All of the above

B

Abatacept does the following:

A. Binds to IL-1

B. Binds to TNF-alpha

C. Binds to the T lymphocyte TCR

D. Binds to CD80/CD86 and blocks the second signal Binds to MHC

E. Class I and prevents first signal

D

Which of the following is NOT a requirement for immunogenicity?

A. Chemical complexity

B. Foreignness

C. Low molecular weight

D. High molecular weight

E. None of the above

C

An immunodeficiency characterized by complete lack of both T and B cells:

A. Chediak-Higashi syndrome

B. SCID

C. X-lined agammaglobulinemia

D. DiGeorge Syndrome

E. Multiple sclerosis

B

These cells have branchlike cytoplasmic projections and can perform phagocytosis

and macropinocytosis and are the most effective APCs

A. Mast cells

B. Dendritic cells

C. Lymphocytes

D. Basophils

E. Eosinophils

B

Infliximab is an inhibitor of the following:

A. IL-1

B. IL-61

C. IL-8

D. TNF-alpha

D

Montelukast is an inhibitor of the following:

A. TNF-alpha

B. Prostaglandins

C. IL-6

D. Leukotrienes

E. All of the above

D

The COX enzymes are responsible for the following:

A. Inhibiting leukotriene metabolism

B. Decreasing vascular permeability

C. Synthesizing prostaglandins from arachidonic acid

D. Decreasing vasodilation

E. None of the above

C

Delayed typed hypersensitivity is the following type:

A. Type I

B. Type II

C. Type IIII

D. Type IV

D

Human A receives an organ (kidney) from human B. What type of graft (transplant) is this?

A. Autograft

B. Isograft

C. Allograft

D. Xenograft

C

Child A has never been immunized against measles. He contracts the measles virus agent, develops the disease and later recovers. What type of acquired immunity is this?

A. Naturally acquired active immunity

B. Artificially acquired active immunity

C. Naturally acquired passive immunity

D. Artificially acquired passive immunity

A