Epinephrine Pharmacology

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A set of vocabulary flashcards summarizing the key pharmacological aspects of Epinephrine.

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11 Terms

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Epinephrine

Also known as adrenaline; a sympathomimetic drug that stimulates alpha and beta receptors.

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Mechanism of Action

Stimulates alpha and beta receptors, increasing heart rate, myocardial contractility, vasoconstriction, and relaxing bronchial smooth muscle.

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Indications for Epinephrine

Includes cardiac arrest, symptomatic bradycardia, anaphylaxis, near death asthma, and croup/stridor.

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Contraindications

None in emergency setting

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Adult Dose for VFib/VTach/PEA/Asystole

1.0 mg IV every 3 - 5 minutes at a concentration of 1:10,000.

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Bradycardia Infusion Dose

2.0 – 10.0 mcg/min.

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Asthma/Anaphylaxis IM Dose

0.3 – 0.5 mg IM/SQ at a concentration of 1:1,000 every 3 - 5 minutes.

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Pediatric Dose for Bradycardia/VFib/VTach/PEA/Asystole

0.01 mg/kg IV.

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Side Effects of Epinephrine

Includes anxiety, headache, hypertension, cardiac dysrhythmias, tremors, chest pain, and nausea/vomiting.

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Precautions when Administering Epinephrine

Use with caution in patients with cardiovascular disease, elderly patients, hypertension, and during pregnancy.