Negative feedback loop

studied byStudied by 0 people
0.0(0)
learn
LearnA personalized and smart learning plan
exam
Practice TestTake a test on your terms and definitions
spaced repetition
Spaced RepetitionScientifically backed study method
heart puzzle
Matching GameHow quick can you match all your cards?
flashcards
FlashcardsStudy terms and definitions

1 / 7

encourage image

There's no tags or description

Looks like no one added any tags here yet for you.

8 Terms

1

What is the negative feedback loop for erythropoiesis?

↓ O2 → Kidney → EPO → Bone Marrow → Erythropoiesis → ↑ RBCs → ↑ O2


A: Erythropoiesis is regulated by a negative feedback loop. When oxygen levels decrease (hypoxia), the kidneys detect the low O2 and release erythropoietin (EPO). EPO stimulates the bone marrow to produce more red blood cells (RBCs), increasing the RBC count and thereby improving the oxygen-carrying capacity of the blood, which restores oxygen levels to normal.

New cards
2

What is the stimulus for the negative feedback loop in erythropoiesis?

Hypoxia (inadequate O2 delivery) due to decreased RBC count, decreased hemoglobin, or decreased O2 availability.

New cards
3

How does altitude training affect erythropoiesis (RBC production)?

It can lead to polycythemia (increased RBC production) due to decreased O2 availability, stimulating erythropoiesis.

New cards
4

How does emphysema affect erythropoiesis?

It can lead to polycythemia due to chronic low oxygen levels in the blood, stimulating erythropoiesis.

New cards
5

What organs release EPO in response to hypoxia?

The kidneys and a small amount of the liver.

New cards
6

What is the function of EPO in erythropoiesis?

EPO stimulates the bone marrow to produce RBCs, increasing the oxygen-carrying capacity of the blood.

New cards
7

What triggers the inhibition of EPO secretion?

Homeostasis is reached when oxygen levels return to normal, signaling the inhibition of EPO secretion.

New cards
8

Where are most RBCs formed in adults?

From the bone marrow in the vertebral column, sternum, and rib cage.

New cards

Explore top notes

note Note
studied byStudied by 18 people
899 days ago
5.0(1)
note Note
studied byStudied by 32 people
794 days ago
5.0(1)
note Note
studied byStudied by 1 person
28 days ago
5.0(1)
note Note
studied byStudied by 103 people
856 days ago
5.0(1)
note Note
studied byStudied by 3 people
761 days ago
5.0(1)
note Note
studied byStudied by 10 people
693 days ago
4.5(2)
note Note
studied byStudied by 39 people
953 days ago
5.0(1)
note Note
studied byStudied by 11 people
776 days ago
5.0(1)

Explore top flashcards

flashcards Flashcard (33)
studied byStudied by 3 people
792 days ago
5.0(1)
flashcards Flashcard (62)
studied byStudied by 5 people
765 days ago
5.0(1)
flashcards Flashcard (82)
studied byStudied by 10 people
56 days ago
5.0(1)
flashcards Flashcard (40)
studied byStudied by 5 people
171 days ago
5.0(1)
flashcards Flashcard (20)
studied byStudied by 115 people
507 days ago
5.0(1)
flashcards Flashcard (25)
studied byStudied by 12 people
468 days ago
5.0(1)
flashcards Flashcard (25)
studied byStudied by 2 people
661 days ago
5.0(1)
flashcards Flashcard (38)
studied byStudied by 38 people
8 days ago
5.0(1)
robot