28 - oral ecology. factors influencing the oral microbial homeostasis. Protective mechanisms of the oral ecosystem

Factors influencing the oral microbial homeostasis

• Temperature

• redox potentials/ anaerobiosis

• pH

• Nutrients - gingival fluid, saliva, residues from host food, products of metabolism of other microbial species

• Host factors - defence mechanisms, hormonal changes, stress, genetic factors

• Antimicrobial agents and inhibitors

Protective mechanisms fo the oral ecosystem

• Epithelial cells - barrier function, innat eimmunity

• Salivary antimicrobial factors

• Mucosal antibodies IgA

• cell mediated immunity T cells

• Removing microorganisms through stimulation of salivary flow

• Specific protection - SIgA

• non specific protection - lysozyme, lactoferrin, salivary peroxidase, histidine rich peptides

• Enamel protection - protects underlying tooths tructure and tissue

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