Ch. 14 Disorders of Platelets, Hemostasis, and Coagulation

This set of flashcards covers key terms and definitions related to disorders of platelets, hemostasis, and coagulation.

Hemostasis

The process of stopping bleeding.

Primary Hemostasis

The process involving platelet aggregation.

Secondary Hemostasis

The process involving fibrin formation that produces a clot (thrombus).

Thrombocytopenia

A condition with platelet levels less than 100,000 cells/uL.

Thrombocytosis

A condition with platelet levels greater than 750,000 cells/uL.

Thrombus

A blood clot that forms in a blood vessel.

Fibrinolysis

The process of breaking down clots.

Calcium and Vitamin K

Essential elements required for the coagulation cascade.

Intrinsic Pathway

Coagulation pathway activated by damage to a blood vessel.

Extrinsic Pathway

Coagulation pathway activated by damage outside the vessel.

DVT

Deep vein thrombosis, a condition where a blood clot forms in a deep vein.

Pulmonary Embolism

A blockage in one of the pulmonary arteries in the lungs, usually due to blood clots.

Antiplatelet Drugs

Medications that prevent arterial clots.

Coagulation Factors

Proteins in the blood that aid in clot formation.

Immune Thrombocytopenic Purpura

An autoimmune disorder resulting in low platelet levels leading to bruising.

Hemophilia

A genetic disorder characterized by deficiency of clotting factors.

Hemolytic Uremic Syndrome

A condition marked by progressive renal failure, hemolytic anemia, and thrombocytopenia.