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Cofactors of EtC
NADH
FMN
FADH2
CoQ
Fe_S
Heme
NADH
free water soluble electron carrier
2 electrons are transfered
oftern the first step in the ETC is oxidation of NADH to NAD+
Flavin Mononucleotide
Flavin adenine Dinucleotide
water soluble but protein bound electron carriers
(flavoproteins)
1 or 2 electron can be transfered
can generate a semiquinone
Coenzyme Q
Free lipid soluble electron carrier
1 or 2 electrons can be transferred
can generate a semiquinone
Iron-sulfur clusters
Prottein bound electron carrier
1 electron
found as 2Fe-2S or 4Fe-4S
electron is transferred to sulfur which is then stabilized by iron
Heme
protein ound electron carrier (cytochromes)
1 electron
consists of a large porphyrin ring and Fe atom in the center