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____________- problematic pattern of use leading to distress/impairment
substance use disorder
_______________: pt has developed a reversible-specific syndrome related to recent ingestion of a substance
Substance use
______________: pt is continuously using a substance without regard to negative consequences including psychological and physiological symptoms
substance use disorder
substance-induced disorder: __________________
-Recent ingestion
-Problematic behavior and psychological effects
-Specific symptoms for each substance
-Symptoms not explained by other condition
intoxication
substance-induced disorder: __________________
-Cessation or reduced in heavy/prolonged use
-The specific symptoms for each substance
-Causes clinically significant stress or impairment
-Symptoms are not explained by other condition
withdrawal
substance-induced disorder: __________________
-Symptoms of a specific mental disorder
-Evidence of BOTH.... Onset within 1 month of intoxication AND withdrawal
-Not explained by other condition
-Not only during delirium
-Significant stress or impairment
Other substance/medication induced mental disorder
Biological etiology (3)
-__________
-Dysfunction in ____________ system
-______
Genetics, reward, pain
Psychological etiology (3)
-_____________
-Psychiatric _____________
-_____________ conditioning
Impulsivity, comorbidity, classical
Sociological etiology (4)
-______ onset of substance use
-_________ hx
-Early __________ to substance use
-______________ strain
Early, trauma, exposure, financial
SUD assessment--- biological domain (9)
Toxicology
Nutrition status
Cardiovascular
GI/liver
Integumentary
Reproductive
Musculoskeletal
Neurologic
Immune
SUD assessment--- psychological domain (4)
Suicidality
Aggression
Mood (depressed, euphoric, anxious, irritable, labile)
Concentration
SUD assessment--- sociological domain: (5)
Relationships and social support
Risk for harm to others
Legal involvement
Access to care
Cultural norms for substance use
Analysis and prioritization-- put these in order:
1. Safety risk withdrawal
2. Safety risk of intoxication
3. Chronic health risks
4. Basic physical needs (food, shelter)
5. Psychiatric comorbidities
6. Suicide risk
2, 1, 6, 4, 5, 3
Non-pharmacologic tx for substance use disorder: GROUP MANAGEMENT INCLUDE:
1
2
3
SBIRT, Peer support, Family support
Non-pharmacologic tx for substance use disorder: INDIVIDUAL MANAGEMENT INCLUDE:
1
2
3
Motivational interviewing, Individual psychotherapy, Contingency management
________________- involves using rewards or incentives as individual reinforcements for positive behaviors, such as abstinence from substance use
type of Individual intervention for SUD
Contingency management
SBIRT= ___________________
is a type of group intervention for SUD
screening, brief intervention, & referral to tx
alcohol withdrawal assessment:
typically begins _________ hrs after last drink and peaks at _________ hrs
6-8, 24-48
these are s/s of ___________ (early or late) alcohol withdrawal:
-Autonomic hyperactivity, tremors, diaphoresis, N/V, headache/fullness, tachycardia, hypertension, piloerection
-Neuropsychiatric (agitation, anxiety, disorientation, confusion, hallucinations-visual or tactile)
Early → 0-48 hr after last drink
these are s/s of ___________ (early or late) alcohol withdrawal:
-Delirium
-Seizures
-Coma
Late → 48-72 hours after last drink- Delirium tremens (DTs)
s/s of Delirium tremens:
1
2
3
Delirium
Seizures
Coma
delirium tremens usually occurs ___________ hr after last drink
48-72
Management: alcohol withdrawal:
1
2
3
4
5
6
VS
Seizure precautions
CIWA assessment
Fall precautions
Re-orientation as needed
Administer medication as ordered: Benzodiazepines
Medication to manage BP/HR
Vitamin infusions
Medications for alcohol use disorder:
___________→ partial opioid agonist, reduces cravings
Naltrexone
Medications for alcohol use disorder:
____________→ MOA unknown but thought modulate GABA
Acamprosate
Medications for alcohol use disorder:
____________→ causes severe N/V if alcohol is ingested
Disulfiram
Medications for alcohol use disorder:
____________ (off-label) → multimodal, exact MOA unknown but thought to increase GABA activity
Topiramate
Management of alcohol intoxication (5):
VS
Resp support as needed
Positioning to prevent aspiration
Fall precautions (risk for injury from falls)
Hydration
ACUTE adverse effects of opioids: _____________
resp depression and sedation
Assessment: opioid intoxication or withdrawal? ________________
VS, Analgesia, Euphoria, Constricted pupils, Sedation, Psychomotor retardation, Urinary retention, Constipation, Pruritus cyanosis
intoxication
Management: Opioid intoxication
1
2
3
1. VS - RR and SpO2
2. Airway management- oxygenation, aspiration risk
3. Administer reversal agent as needed- narcan
Assessment: opioid intoxication or withdrawal? ________________
VS→ high HR, high BP
Dilated pupils
Yawning
Diaphoresis
Lacrimation
Diarrhea
Stomach cramping, N/V
Myalgia
Insomnia
Anxiety
Psychomotor agitation
withdrawal
Management: Opioid withdrawal
1. __________ assessment protocol
2. Maintain ___________
3. __________ care
4. Supportive __________
Cows, hydration, Perianal, meds
ACUTE adverse effects of stimulant pharmacology:
1
2
3
4
5
hyperthermia, cardiac arrhythmia, MI, seizure
Stimulant use----- intoxication or withdrawal? ________________
-high HR, BP, RR
- Pupil dilation, blurred vision, nystagmus
-diaphoresis
-insomnia
-psychosis(paranoia, tactile and visual hallucinations)
-mood lability
-agression
-Reduced appetite
-Increased energy
intoxication
Stimulant use----- intoxication or withdrawal? ________________
-Fatigue
-Anxiety
-Impaired cognition
-Mood swings confusion
-Insomnia
-Vivid dreams
withdrawal
Management of stimulant intoxication (6)
CV monitoring
Maintain safety of pt and others
Maintain hydration and nutrition
Reduce environment stimuli
Encourage rest
Therapeutic communication (validate emotions, do not argue with delusions, reassure physical safety)
ACUTE adverse effects of PCP:
1
2
3
4
cardiac arrhythmia, seizure, coma, rhabdomyolysis
PCP intoxication or withdrawal? ________________
-no clinical manifestations
withdrawal
PCP intoxication or withdrawal? ________________
High HR and BP
Pupil dilation, nystagmus
Insomnia
Psychosis (paranoia, tactile & visual hallucinations)
Mood lability
Aggression
Increased energy
Analgesia
Impulsivity
Muscle rigidity
intoxication
Management of PCP intoxication (6)
Monitor CV status, maintain safety of pt and others, monitor creatine kinase, hydration, reduce environment stimuli, encourage rest
Medications for opioid use disorder (MOUD) (3):
Methadone, buprenorphine, naltrexone
Pharmacologic tx for nicotine withdrawal (2):
Bupropion, Varenicline
Management of nicotine withdrawal (5):
Nicotine replacement therapy (patch, gum, nasal spray)
Offer candy/gum/mints
Relaxation techniques
Dirstractio
Pharmacologic tx
Assessment for moderate alcohol intoxication (8):
Disinhibition
Lack of coordination
Unsteady gait
Slurred speech
Slowed reaction time
Impaired attention
Blurred vision
Nystagmus
Assessment for severe alcohol intoxication (3)
N/V, resp depression, coma
Substances that have medically serious withdrawal:
Stimulants, steroids, inhalants (nicotine), sedatives/hypnotics
SUD Harm reduction:
- always carry ___________
- utilize __________
-Use only ___________
-Never use ___________
-Start with small amount and go slow
-Use less after period of ___________
-Supervised consumption sites
-co-prescribe___________ with opiates
-_________ screening, tx, and education
Narcan, Test strips, one substance at a time, alone, abstinence or reduced tolerance, narcan, STI
Harm reduction: inhalation---Smoking
-Use mouthpiece and filter with pipe
-Don't share mouthpiece or pipe
-Avoid use of homemade pipes
Harm reduction: inhalation---snorting
-Rotate nostrils
-Use sterile straw
-Grind substance
-Use water or nasal spray