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organelles
membrane-enclosed structures within a eukaryotic cell
cytosol
a jellylike substance where organelles and other components are found
eukaryotic cell
Cell with a nucleus and membrane bound organelles
prokaryotic cell
Cell with no nucleus nor membrane bound organelles
nucleoid region
a non-membrane-enclosed region of the cell where prokaryotic DNA is found
cytoplasm
the region in a cell between the cell membrane and nucleus; it contains the cell structures and oganelles
plasma membrane
The selective barrier that surrounds a cell; it controls what enters and leaves the cell
nucleus
chromosome-containing part of a eukaryotic cell
nuclear envelope
encloses the nucleus to separate its contents from the cytoplasm
ribosomes
made of ribosomal RNA and protein, synthesize proteins
endomembrane system
membranes that divide the cell into organelles such as the nuclear membrane, the endoplasmic reticulum, the Golgi apparatus, lysosomes, vesicles, and the cell membrane.
endoplasmic reticulum (ER)
accounts for more than half of total membrane in many eukaryotic cells, continuous with the nuclear envelope
smooth ER
portion of the endoplasmic reticulum free of ribosomes, synthesize lipids, detoxifies the cell, and regulates calcium levels
rough ER
portion of the endoplasmic reticulum studded with ribosomes, produce and transport membrane and secretory proteins
glycoproteins
proteins with covalently-bonded carbohydrates that play a role in cell to cell interaction
transport vesicles
vesicles in transit from one part of the cell to another
Golgi apparatus
stack of membranes that modifies, sorts, and packages proteins from the endoplasmic reticulum
lysosome
membranous sac of hydrolytic enzymes, which the cell uses to digest unwanted materials
phagocytosis
the process by which a cell engulfs a solid particle
food vacuoles
formed by phagocytosis, pinches off from plasma membrane and encloses a food particle
contractile vacuoles
pump excess water out of the cell to maintain a suitable concentration of ions and molecules in the cell
central vacuole
the largest organelle in a plant cell. It is surrounded by the tonoplast and functions to hold materials and wastes. It also functions to maintain the proper pressure within plant cells
mitochondria
chemically convert chemical (food) energy into usable ATP energy through cellular respiration
chloroplasts
contain chlorophyll which help absorb solar energy in order to convert carbon dioxide and water into sugars during photosynthesis
cristae
infoldings in the inner membrane of the mitochondria
mitochondrial matrix
compartment of the mitochondrion, enclosed by the inner membrane, contains enzymes and substrates for the citric acid cycle
plastids
manufacture and store important chemical compounds used by the cell such as pigments, oils, and starches
thylakoids
flattened and interconnected sacs found in chloroplasts. The light dependent stage of photosynthesis occurs on the membranes of these sacs
granum
stacks of thylakoids
stroma
fluid outside the thylakoids, contains chloroplast DNA, ribosomes, and enzymes. The light independent stage of photosynthesis occurs in this area
cytoskeleton
a network of fibers bracing the cytoplasm
microtubules
hollow rods of protein, support the cell and moves organelles within the cell
centrosome
a region located near the nucleus where micro-tubules grow from; important in cell division
centrioles
cylindrical organelle near the nucleus in animal cells, occurring in pairs and involved in the development of spindle fibers in cell division
flagella
a long tail-like structure that aids in cell movement
cilia
a short hair-like structures that enable movement of cells or movement of materials outside a cell, utilizes a back-and-forth motion
microfilaments
the thinnest part of the cytoskeleton, are used to give shape to the cell and support all of its internal parts
cell wall
extracellular structure specific to plant cells, protects the cell, maintains its shape, and prevents excessive water uptake
extracellular matrix (ECM)
where animal tissue cells are embedded, consists of protein and polysaccharides
collagen
most common glycoprotein in the ECM, forms strong fibers outside the cells
gap junctions
intercellular junction in animal tissues that provide cytoplasmic channels from one cell to an adjacent cell, similar to plasmodesmata in plants
Plasma membrane
The boundary that separates the living cell from its surroundings
Selective permeability
_________ ____________ is a characteristic of cell membranes that means what passes in and out is regulated. It allows some substances to cross the membrane more easily than others.
Amphipathic
Having characteristics of being hydrophobic and hydrophilic, such as a phospholipid.
Phospholipid
The basic structural component and most abundant lipid of cell membranes is ____________.
Fluid Mosaic Model
Describes a membrane as a fluid structure with a "mosaic" of various proteins embedded in it.
Osmosis
The diffusion of water across a selectively permeable membrane.
Diffusion
A passive process that involves the movement of substances or molecules from high solute concentration to low. It is also the tendency for molecules to spread out evenly into the available space.
Active transport
Uses energy (usually in the form of ATP) to move solutes against their concentration gradients and to maintain concentration gradients that differ from their surroundings, i.e. sodium-potassium pump.
Electrogenic pump
An ion transport protein that generates voltage across a membrane.
Endocytosis
The cell takes in macromolecules by forming vesicles from the plasma membrane.
Phagocytosis
Also known as cellular eating. A cell engulfs a particle in a vacuole.
Pinocytosis
Also known as cellular drinking. Molecules dissolved in droplets are taken up when extracellular fluid is "gulped" into tiny vesicles.
Receptor-mediated endocytosis
Special receptor proteins catch molecules and bring them into the cell against a concentration gradient
Exocytosis
Transport vesicles migrate to the
membrane, fuse with it, and release their contents outside the cell
Peripheral proteins
Proteins bounded to the surface of the membrane.
Integral proteins
Proteins that penetrate the hydrophobic core.
Transmembrane proteins
Proteins that span the membrane.
What are the 6 major functions of membrane proteins?
Transport, enzymatic activity, signal transduction, cell-cell recognition, intercellular joining, and attachment to the cytoskeleton and extracellular matrix (ECM)
Hydrophobic (nonpolar) molecules
Can dissolve in the lipid bilayer and pass through the membrane rapidly, such as hydrocarbons.
Hydrophilic molecules
Do not cross the membrane easily, such as ions and polar molecules.
Transport proteins
Allow passage of hydrophilic substances across the membrane.
Channel protein
A type of transport protein that has a hydrophilic channel that certain molecules or ions can use as a tunnel.
Aquaporins
Channel proteins that facilitate the passage of water.
Carrier protein
A type of transport protein that binds to molecules and changes shape to shuttle them across the membrane.
Passive transport
The diffusion of a substance across a membrane with no energy investment.
Concentration gradient
The region along which the density of a chemical substance increases or decreases.
Tonicity
The ability of a surrounding solution to cause a cell to gain or lose water.
Isotonic solution
Solute concentration is the
same as that inside the cell; no net water
movement across the plasma membrane.
Hypertonic solution
Solute concentration is
greater than that inside the cell; cell loses water.
Hypotonic solution
Solute concentration is less
than that inside the cell; cell gains water.
Osmoregulation
The control of solute concentrations and water balance that is a necessary adaptation for life in such environments.
Turgid
A plant cell in a hypotonic solution swells until the
wall opposes uptake; the cell is now turgid (firm).
Facilitated diffusion
Transport proteins speed the passive movement of molecules across the plasma membrane. I describe the passive assistance of a transport protein to move substances from high solute concentration to low. I require no energy expenditure, instead using transport proteins to pass through membranes. What am I?
Ion channels
Channel proteins that facilitate the diffusion of ions.
Gated channel
A type of ion channel that opens or closes in response to a stimulus.
Electrochemical gradient
Two combined forces that drive the diffusion of ions across a membrane: A chemical force (the ion's concentration gradient) and an electrical force (the effect of the membrane potential on the ion's movement).
Sodium-potassium pump
The major electrogenic pump of animal cells
What is the purpose of electrogenic pumps?
To help store energy that can be used for cellular work
Bulk transport
Occurs by exocytosis and endocytosis and requires energy
How do small molecules and water enter or leave the cell?
Through the lipid bilayer or via transport proteins
How do large molecules, such as polysaccharides and proteins, cross the membrane?
In bulk via vesicles
What are the 3 types of endocytosis?
Phagocytosis, pinocytosis, and receptor-mediated endocytosis
Adenosine Triphosphate (ATP)
compound used by cells to store and release energy
Cell Theory
fundamental concept of biology that states that all living things are composed of cells; that cells are the basic units of structure and function in living things; and that new cells are produced from existing cells
Three domains of life
Bacteria, Archaea, Eukarya
Prokaryote
A unicellular organism that lacks a nucleus and membrane bound organelles
Eukaryote
A cell that contains a nucleus and membrane bound organelles
Ribosomes
site of protein synthesis; 70s size in prokaryotes and 80s size in eukaryotes
Mitochondria
An organelle found in large numbers in most cells, in which the biochemical processes of cellular respiration and energy production occur. Produces ATP.
Lysosome
An organelle containing digestive enzymes
Vacuole
Cell organelle that stores materials such as water, salts, proteins, and carbohydrates
Peroxisome
organelle with various specialized metabolic functions; produces hydrogen peroxide as a by-product, then converts it to water
chloroplast
captures sunlight for energy and contains chlorophyll to give plants a green color
Surface area to volume ratio
a variable that decreases as cells grow, so that it sets a limit to the size of cells.
signal transduction
1 type of function for membrane proteins. Membrane proteins with a binding site has a specific shape that fits the shape of a chemical messenger
Enzymatic Activity
1 type of membrane protein function. Proteins are built into the membrane may be an enzyme with its active site exposed to substances in the adjacent solution. Sometimes molecule enzymes are organized as a team that carries out multiple steps of a metabolic process.
cell-cell recognition
1 function of membrane proteins; some glycoproteins serve as identification tags that are specifically recognized by other cells.
Intracellular Joining
1 function of membrane proteins; membrane proteins of adjacent cells may hook together in various kinds of junctions (i.e. gap junctions)
Cell Attachement
1 function of membrane proteins; proteins can adhere to the ECM and can coordinate extracellular and intracellular changes.