PCL #1 Quiz #1 Drugs #1-34

Amoxicillin

Brand: Amoxil, Moxatag

Class: B-Lactam Antibiotic

Indication:

Amoxicillin/Clavulanate

Brand: Augmentin

Class: B-Lactam Antibiotic

FDA Indication:

1. Acute otitis media

2. Lower respiratory tract infection

3. Pharyngitis

4. Tonsillitis

5. Streptococcal pharyngitis, H.pylori Gi tract

Azelastine

Brand: Astelin, Astepro

Class: Nasal Antihistamine

Indication:

1. Perennial allergic rhinitis

2. Seasonal allergic rhinitis

3. Vasomotor rhinitis 

Azithromycin

Brand: Zithromax, Z-Pak

Class: Macrolide Antibiotic

Indication: 

1. Acute infective exacerbation of COPD, skin or tissue infection 

2. Bacterial sinusitis

3. Chancroid, nongonococcal cervicitis, nongonococcal urethritis

4. Community-acquired pneumonia

5. Sexually transmitted infections

6. Streptococcal pharyngitis 

Benazepril

Brand: Lotensin

Class: ACE-I, Antihypertensive

Indication: 

1. Hypertension

Benzonatate

Brand:Tessalon, Perles

Class: Antitussive

Indication:

1. Cough

Canagliflozin

Brand: Invokana

Class: Antidiabetic agent, Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitor

Indication:

1. Diabetes mellitus, Type 2

Chlorothalidone

Brand: Hygroton, Thalitone

Class: Thiazide Diuretic

Indication: 

1. Hypertension, Edema

Clarithomyrocin

Brand: Biaxin

Class: Macrolide Antibiotic

Indication: 

1. Acute infective exacerbation

2. Community-acquired pneumonia, skin infection, sinusitis, pharyngitis 

3. Disseminated infection due to M. avium-intracellulare group, prophylaxis-HIV infection, primary prevention and treatment

4. H. pylori GI tract infection

5. Streptococcal pharyngitis (group A)

6. COPD, acute exacerbation

COVID-19 mRNA Vaccines

Brand: Comirnaty, Spikevax

Class: Covid mRNA Vaccine

Indication: 

Dapaglifozin

Brand: Farxiga

Class: Antidiabetic Agent, Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitor

Indication:

1. Diabetes mellitus

2. Heart failure with reduced ejection fraction

Diphteria Toxoid

Brand: Adacel, Boostrix, Daptacel, Infanrix, Tenviac

Class: Vaccine, Inactivated, Bacterial

Indication: Prevention of diptheria

Dulaglutide

Brand: Trulicity

Class: Antidiabetic Agent, Glucagon-Like Peptide-1 Receptor Antagonist

Indication: Diabetes mellitus 

Enalapril

Brand: Vasotec

Class: ACE-I, Antihypertensive

Indication: Heart failure, Hypertension, Kidney disease, nondiabetic

Epinephrine Auto-Injector

Brand: Adrenaclick, Auvi-Q, EpiPen, EpiPenJr

Class: Alpha/Beta Antagonist, Anaphylaxis Agent

Indication: Emergency treatment of acute anaphylaxis due to allergic reactions

Exenatide

Brand: Byetta, Bydureon

Class: Glucagon-Like Peptide 1 Receptor Antagonist

Indication: Diabetes mellitus type 2

Ezetimibe

Brand: Zetia

Class: Antihyperlipidemic, Cholesterol Absorption Inhibitor

Indication: 

1. Familial hypercolesterolemia-homozygous, with atorvastatin or simvastatin

2. Mixed hyperlipidemia

3. Primary hypercholesterolemia 

Fenofibrate

Brand: Antara, Fenoglide, Lipofen, Lofibra, Tricor, Trilipix

Class: Antihyperlipidemic

Indication:

1. Hypercholesterolemia, primary hypercholesterolemia, or mixed dyslipidemia

2. Hypertriglyceridemia, Frederickson types 4 and 5 hyperlipidemia 

Fidaxomicin

Brand: Dificid

Class: Macrolide Antibiotic

Indications:

1. C. difficile infection

Fosinopril

Brand: Monopril

Class: ACE-I, Antihypertensive

Indication

1. Heart failure, hypertension

Gemfibrozil

Brand: Lopid

Class: Antihyperlipidemic, Fibric Acid

Indication: 

1. Coronary arteriosclerosis; prophylaxis-familial combined hyperlipidemia

2. Familial type V hyperlipoproteinemia-Fredrickson type IV hyperlipoproteinemia

Haemophilus Influenzae, Serotype B Vaccine

Brand: ActHIB, Hiberix, PedvaxHIB

Class: Vaccine, Inactivated, Bacterial

Indication: 

1. Prevention of invasive H.influenzae type B infection

Hydralazine

Brand: Apresoline

Class: Peripheral Vasodilator

Indication:

1. Hypertension

Hydrochlorothiazide

Brand: N/A

Class: Thiazide Diuretic, Antihypertensive

Indication:

1. Edema, adjunct

2. Hypertension

Liraglutide

Brand: Victoza, Saxenda

Class: Glucagon-Like Peptide-1-Receptor Antagonist

Indication:

1. Diabetes mellitus type 2

2. Chronic weight measurement

Lisinopril

Brand: Prinivil, Zestril

Class: ACE-I, Antihypertensive

Indication: 

1. ST-Segment Elevation MI

2. Heart failure with reduced ejection fraction

3. Hypertension

Meclizine

Brand: Antivert, Bonine, Dramamine

Class: Antihistamine, Antiemetic

Indication: 

1. Motion sickness

2. Verigo

Meningococcal Vaccine

Brand: MenQuadfi, Menveo, Trumenba, Bexsero

Class: Vaccine, Inactivated, Bacterial

Indication:

1. Prevention of invasive meningococcal disease caused by serotypes A,C,Y,W-135

2. Prevention of invasive meningococcal disease caused by serotype B

Niacin

Brand: Niaspan, Slo-Niacin

Class: Antihyperlipidemic

Indication:

1. Coronary arteriosclerosis, hypercholesterolemia

2. Dyslipidemia

3. Acute myocardial infection, secondary prophylaxis

Penicillin

Class: Antibiotic

Indication:

1. Bacterial endocarditis, prophylaxis in patients with congenital heart disease or rheumatic/acquired valvular heart disease

2. Otitis media, mild-moderate, pneumococcal

3. Streptococcal pharyngitis

4. Erysipelas, mild infection or step-down therapy

Pertussis Vaccine

Brand: Daptacel, Adacel, Boostrix, Infanrix

Class: Vaccine, Inactivated, Bacterial

Indication:

1. Prevention of pertussis

Pneumococcal Vaccine

Brand: Prevnar 13, Prevnar 20, Pneumovax23, Vaxneuvance

Class: Vaccine, Inactivated, Bacterial

Indication:

1. Prevention of invasive pneumococcal disease 

Promethazine

Brand: Phenergan

Class: Phenothiazine Antihistamine

Indication:

1. Motion sickness

2. Allergy

3. Nausea and vomitting

Spironolactone

Brand: Aldactone, CaroSpir

Class: Potassium-Sparing Diuretic, Selective Aldosterone Blocker

Indication:

1. Heart failure, NYHA class III-IV

2. Edema associated with heart failure

3. Nephrotic syndrome

4. Hypertension

5. Hypokalemia