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R. C. Punnett conducted experiments on the inheritance of traits in the sweet pea, Lathyrus odoratus. In one experiment, he crossed two different true-breeding sweet pea plant strains, one with erect petals and long pollen, and the other with hooded petals and round pollen. All the offspring (F1F1 generation) had erect petals and long pollen (Figure 1).
Next, Punnett allowed the F1F1 generation to self-fertilize and recorded the phenotypes of their offspring. The data are shown in Table 1.
Which of the following best explains how the sweet pea plants in the parental generation produce F1F1 offspring with 14 chromosomes?
Meiosis I and II lead to the formation of cells with 7 chromosomes. During meiosis I, homologous chromosomes separate. During meiosis II, sister chromatids separate. Two cells combine during fertilization to produce offspring with 14 chromosomes.
(same info as question 1)
Which of the following questions would be most useful to researchers trying to determine the role of meiosis in the F2F2 phenotypic frequencies?
What is the recombination frequency between the genes for petal shape and pollen shape?
(same info as question 1)
How many degrees of freedom should be used when looking up the critical value for a chi-square analysis of the ratios of phenotypes observed among the F2 offspring versus the expected phenotypic ratio assuming independent assortment?
3
For sexually reproducing diploid parent cells, which of the following statements best explains the production of haploid cells that occurs in meiosis but not in mitosis?
Separation of chromatids occurs once, and there are two rounds of cell division in meiosis.
Which of the following best explains a distinction between metaphase I and metaphase II?
Homologous pairs of chromosomes are aligned during metaphase I, but individual chromosomes are aligned during metaphase II.
In anaphase II of meiosis, cohesion between the centromeres of sister chromatids is maintained while homologous chromosomes migrate to opposite poles of the cell along the meiotic spindle as represented in Figure 1.
A compound that prevents the separation of the homologous chromosomes in anaphase II is being studied. Which of the following questions can be best answered during this study?
Is there a pattern to the movement of homologous chromosomes in the presence of this compound?
Based on Figure 1, which of the following questions could best be addressed?
Does synapsis of homologous chromosomes in the parent cell contribute to an increase in genetic diversity in the daughter cells?
Researchers performed a dihybrid cross with coffee bean plants to investigate whether the inheritance of two traits (height and stem circumference) follows Mendel's law of independent assortment. The data for the F2 generation are presented in Table 1.
Which of the following is closest to the calculated chi-square (χ2)(χ2) value for the data presented in Table 1?
72.01
Researchers hypothesized that red eye color in Japanese koi, a type of fish, is due to a mutation. To study the inheritance of red eye color in koi, the researchers conducted breeding experiments over several generations. The results are summarized in Figure 1.
Based on the data in Figure 1, which of the following is the best prediction of the mode of inheritance of red eyes in Japanese koi?
The allele for red eyes is inherited in an autosomal dominant pattern.
In corn plants, purple kernel color is dominant to yellow kernel color, and smooth kernels are dominant to wrinkled kernels. Researchers carried out a genetics experiment to investigate whether the genes controlling kernel color and kernel texture segregate independently. In their experiment, the researchers crossed two corn plants that were each heterozygous for both kernel color and kernel texture. The results of the experiment are presented in Table 1.
Using a significance level of p=0.05, which of the following statements best completes a chi-square goodness-of-fit test for a model of independent assortment?
The calculated chi-square value is 3.91, and the critical value is 7.82. The null hypothesis cannot be rejected.
Several members of a family are found to involuntarily sneeze when exposed to bright lights, such as sunlight. Following analysis of the condition in the family, a doctor predicts that the symptoms have an underlying genetic basis. A pedigree of the family is shown in Figure 1.
For this condition, which of the following modes of inheritance is most consistent with the observations?
autosomal dominant
In pea plants, purple flower color is dominant to red flower color and long pollen grains are dominant to round pollen grains. Researchers crossed two pure-breeding lines of the pea plants to investigate whether the genes controlling flower color and pollen shape segregate independently. The procedure for the genetics experiment is summarized in Figure 1.
Which of the following tables best shows the expected values in the F2 generation for a chi-square goodness-of-fit test for a model of independent assortment?
purple, long - 1199
purple, round - 400
red, long - 400
red, round - 133
Glycolysis is a metabolic pathway that converts glucose into pyruvate and is observed in each of the three domains. The hexokinase family of enzymes is required during glycolysis to phosphorylate six-carbon sugars. Researchers designed a general hexokinase inhibitor that is effective in the neurons of rats.
Which of the following best predicts the effect of adding this inhibitor to a culture of plant cells?
Plant cells will be unable to perform glycolysis due to the inhibitor and will die.
Students carry out a genetics experiment to investigate the inheritance pattern of the white-eye trait in fruit flies. In the experiment, the students cross a red-eyed female with a white-eyed male to produce an F1 generation. The students observe that all the flies in the F1F1 generation have red eyes. The students then allow the F1 flies to mate and produce an F2 generation. The students will use the F2 data to perform a chi-square goodness-of-fit test based on a null hypothesis of autosomal recessive inheritance. The observed and expected values for the chi-square goodness-of-fit test are shown in Table 1.
The students plan to use a significance level of p=0.01. Which of the following is the most appropriate critical value for the students to use in their chi-square goodness-of-fit test?
11.34
Four trials measuring recombination frequency between gene R and gene L were conducted, and the results are shown in Table 1.
The mean map distance between gene R and gene L is closest to which of the following?
28 map units
Rubber rabbitbrush plants display heritable variation in plant height and insect-induced gall formation. In a field study, researchers investigated the relationship between plant height and gall number for the rubber rabbitbrush plants in a natural population. The researchers used the data they collected to perform a chi-square test of independence. The null hypothesis for the chi-square test was that plant height and gall number are independent. The data for the chi-square test are presented in Table 1.
The researchers calculated a chi-square value of 29.25. If there are three degrees of freedom and the significance level is p=0.05, which of the following statements best completes the chi-square test?
The critical value is 7.82, and the null hypothesis can be rejected because the calculated chi-square value is greater than the critical value.
A true-breeding variety of wheat that produces deep-red-colored grain was crossed with a true-breeding variety that produces a white-colored grain. The resulting F1F1 offspring all had medium-red-colored grain. Five crosses of the F1F1 plants were all grown under the same conditions and resulted in plants with a variety of grain color, as indicated in Table 1.
Which of the follow indicates the mean number per cross of F2F2 plants producing medium-red grain and correctly explains the distribution of the phenotypes?
The mean number of medium-red phenotypes per cross is 20.8. The distribution of phenotypes suggests that multiple genes are involved in grain color determination.
Two fruit fly mutations are ebony body (e)(e) and sepia eyes (s)(s). Four different students performed dihybrid crosses with flies that were heterozygous with a mutant allele and a wild-type allele for both genes (EeSsĂ—EeSs). The results are shown in Table 1.
The mean number of fruit flies per student that are homozygous recessive for both genes is closest to which of the following?
29.0
Himalayan rabbits are a breed of rabbits with highly variable fur color. If genetically similar rabbits are raised in environments that have different temperature conditions, the rabbits can have different color patterns.
Which of the following statements best explains how the fur color can be different in Himalayan rabbits raised under different temperature conditions?
The environment determines how the genotype is expressed.
The tadpoles of Mexican spadefoot toads are known to exhibit phenotypic plasticity depending on food availability. Tadpole mouthparts can vary significantly, prompting researchers to categorize them as either omnivore-morph or carnivore-morph. Carnivore-morph tadpoles are larger and have mouthparts that are better suited for predation. Remarkably, carnivore-morph tadpoles can change into omnivore-morph tadpoles when the food supply changes.
Which of the following best describes an advantage of the phenotypic plasticity displayed by the tadpoles?
It gives the tadpoles increased versatility with respect to diet.
When a mustard plant seedling is transferred to an environment with higher levels of carbon dioxide, the new leaves have a lower stomata-to-surface-area ratio than do the seedling's original leaves.
Which of the following best explains how the leaves from the same plant can have different stomatal densities when exposed to an elevated carbon dioxide level?
Leaf growth is promoted through increased photosynthesis, but the genetically regulated rate of stomatal production is not altered, leading to a decrease in stomatal density.
Which of the following best predicts the effect of the chromosomal segregation error shown in Figure 1?
Half of the resulting gametes will have the correct number of chromosomes, and the other half will have an incorrect number of chromosomes.
Sex chromosomes determine the phenotype of sex in humans. Embryos containing XX chromosomes develop into females, and embryos containing XY chromosomes develop into males. The sex chromosomes separate during meiosis, going to different gamete cells.
A woman is heterozygous for the X-linked recessive trait of hemophilia AA. Her sex chromosomes ca An be designated as XHXh. During meiosis the chromosomes separate as shown in Figure 1.
If the woman and a man with normal clotting function have children, what is the probability of their children exhibiting hemophilia A?
50 percent for sons, 0 percent for daughters
Huntington's disease has been traced to the number of CAG repeats in the HTT gene, which is located on chromosome 4. The phenotypic influence of individual alleles with different numbers of repeats is shown in Table 1.
Which of the following is most likely the immediate cause of the first appearance of Huntington's disease in a person?
An allele with more than 39 CAG repeats was inherited by the affected person.