Anti-Muscarinic Drugs / Nicotinic Receptors (Part 3)

Atropine type and use

Anti-muscarinic, Pupil dilation (atropa belladonna)

Antimuscarinic Drugs: A Benz is Scool

Atropine, Benztropine, Ipratropium, Scopolamine

Mydriasis is what? contraindicated in?

Pupil dialtion, glaucoma

Cycloplegia is what?

Loss of lens acomodation

Scopolamine uses

Motion sickness

Anticholinergic Contraindications

Glaucoma, Benign Prostate Hypoplasia, Urinary Obstruction, intestinal obstruction, cardiovascular disease

“Flying Death” Paralytic Agent for muscle nicotinic recerptors

Curare

Varenicline (Chantix)

Partial agonist for nicotinic receptor, long half life

What receptors does Curare block?

Nm

What does Succinylcholine do?

Depolarize / cause twitching

Phase 1 or 2 block used therapeutically?

Phase 1