HORMONES

Hormones

chemical messengers from hypothalamus and pituitary gland

Pituitary gland

aka Hypophysis

Growth hormone

promotes growth of body tissues

Prolactin-releasing hormone

stimulate milk production in mammary glands

Thyroid-releasing hormone

for synthesis of thyroid hormone (T3, T4)

Gonadotropin-releasing hormone

• Follicle stimulating hormone (FSH)

• Luteinizing hormone

Adrenocorticotropin

for cortisol hormones

Adenohypophysis

other name for Anterior Pituitary gland

Neurohypophysis

other name for Posterior Pituitary gland

Vasopressin

anti-diuretic hormone

Diabetes Insipidus

abnormal large volume of urine

• hypernatremia

• polydipsia

• polyuria

symptoms of diabetes insipidus

Oxytocin

induces contraction of uterus

Growth hormone

mediated by regulating the production in peripheral tissues of IGF-1

Somatropin

the rDNA derived form of GH (for XO genotype)

Mecasermin

the rDNA derived form of IGF-1

Rinfabate

the rDNA derived form of IGFBP-3 (insulin-like growth factor binding protein)

GH agonist

• somatropin

• mecasermin

• rinfabate

• Octreotide

• Lanreotide

long-acting synthetic analogs of somatostatin, are used to treat acromegaly, carcinoid, gastrinoma, glucagoonoma, and other endocrine tumors

Somatostatin

asdf 14-amino acid peptide, inhibits the release of GH, glucagon, insulin, and gastrin

Bromocriptine

inhibits GSH release at high doses

Pegvisomant

GH receptor antagonist approved for treatment of acromegaly

Oxytocin

effective stimulant of uterine contraction and is used intravenously to induce or reinforce labor.

Atosiban

an antagonist of the oxytocin receptor used to suppress preterm labor

Vasopressin (Antidiuretic Hormone [ADH])

prevents diuresis and regulate release of coagulation factor VIII and Willebrand factor

Desmopressin

a selective agonist of V2 receptors with long DOA and minimal pressor effect

anterior

Anterior or Posterior: Gonadotropin

Posterior

Anterior or Posterior: Vasopressin

anterior

Anterior or Posterior: Prolactin-releasing hormone

anterior

Anterior or Posterior: Growth hormone

posterior

Anterior or Posterior: Oxytocin

anterior

Anterior or Posterior: Thyroid-releasing hormone

anterior

Anterior or Posterior: Adrenocorticotropin