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Reserpine
Indication for HTN and psychosis
Reserpine
Inhibit VMAT —> deplete storage of NE —> low BP
Tyramine, amphetamines, and ephedrine
Poor agonist at adrenergic receptors
Tyramine, amphetamines, and ephedrine
High affinity for NET (NE transporter) and VMAT displace NE increase release of NE