Amiloride – Potassium-Sparing Diuretic

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Last updated 1:30 AM on 2/24/26
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5 Terms

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Mechanism of action


Prevents sodium reabsorption in distal tubule → retains potassium.

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Primary therapeutic use

  • Hypertension

  • Edema (with loop/thiazide)

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Major / deadly side effects:

Hyperkalemia

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Critical teaching points

  • Avoid potassium supplements

  • Monitor labs

  • Take in morning

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Easy memory

K⁺ saver

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