Ch. 4 Brain Development

What are Amyloid Plaques?

Amyloid plaques are abnormal clumps of protein fragments that accumulate between neurons in the brains of people with Alzheimer's disease, disrupting cell function and signaling.

What are neurofibrillary tangles?

Neurofibrillary tangles are twisted strands of a protein called tau that accumulate inside neurons in the brains of individuals with Alzheimer's disease, contributing to cell death and cognitive decline.

Dementia

Dementia is a general term for a decline in cognitive function severe enough to interfere with daily life, often characterized by memory loss, impaired reasoning, and changes in behavior.

Location in which researchers have observed neurogenesis?

The hippocampus, especially in the denate gyrus.

Neurogenesis: mitosis produces neurons from non-neuronal cells within the ventricular zone, the innermost layer of the neural tube.