Anti-histamines/ Eicosanoid analogues

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Last updated 8:11 PM on 1/8/26
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21 Terms

1
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which complement proteins trigger inflammation

C3a, C5a

2
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what is the enzyme that converts histidine to histamine

histidine decarboxylase

3
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how many types of histamine receptor are there

4

4
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which histamine receptor is mainly responsible for vascular effects

H1

5
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which receptor mediates smooth muscle contraction during inflammatory response

H1

6
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which receptor mediates cardiovascular effects during inflammatory response

H2

7
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which receptor mediates gastric acid release during inflammatory response

H2

8
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which receptor mediates vasodilation during inflammatory response

H1

9
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what is an example of a first generation H1 antagonist

diphenhydramine

10
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what is an example of a second generation H1 antagonist

cetirizine

11
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what are two examples of H2 antagonists

cimetidine, ranitidine

12
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which cells secrete protons in GI tract

parietal cells

13
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which cells secrete histamine in GI tract

enterochromaffin like cells

14
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which receptors are found on parietal cells

H2

15
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what are two examples of proton pump inhibitors

omeprazole, lansoprazole

16
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what is an example of a PGE1 analogue

misoprostol

17
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what is this PGE1 analogue used for

labour induction

18
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what is an example of a PGF2alpha analogue

bimatoprost

19
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what is this PGF2alpha analogue used for

glaucoma

20
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what is an example of a PGI2 analogue

iloprost

21
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what is this PGI2 analogue used for

pulmonary arterial hypertension