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which complement proteins trigger inflammation
C3a, C5a
what is the enzyme that converts histidine to histamine
histidine decarboxylase
how many types of histamine receptor are there
4
which histamine receptor is mainly responsible for vascular effects
H1
which receptor mediates smooth muscle contraction during inflammatory response
H1
which receptor mediates cardiovascular effects during inflammatory response
H2
which receptor mediates gastric acid release during inflammatory response
H2
which receptor mediates vasodilation during inflammatory response
H1
what is an example of a first generation H1 antagonist
diphenhydramine
what is an example of a second generation H1 antagonist
cetirizine
what are two examples of H2 antagonists
cimetidine, ranitidine
which cells secrete protons in GI tract
parietal cells
which cells secrete histamine in GI tract
enterochromaffin like cells
which receptors are found on parietal cells
H2
what are two examples of proton pump inhibitors
omeprazole, lansoprazole
what is an example of a PGE1 analogue
misoprostol
what is this PGE1 analogue used for
labour induction
what is an example of a PGF2alpha analogue
bimatoprost
what is this PGF2alpha analogue used for
glaucoma
what is an example of a PGI2 analogue
iloprost
what is this PGI2 analogue used for
pulmonary arterial hypertension