RBC morphology and Inclusions

Acanthocytes

Echinocytes

Elliptocyte

Schistocytes

Blister Cells

Helmet Cells

Drepanocytes (Sickle Cells)

Spherocytes

Stomatocytes

Codocytes (Target Cells)

Dacryocytes (Teardrop Cells)

Hypochromic

Polychromasia

Rouleaux

Autoagglutination

Hemoglobin C crystals

Hemoglobin SC crystals

Howell-Jolly Bodies

Basophilic Stippling

Cabot Ring

Pappenheimer Bodies

Heinz Bodies

Anisocytosis

variation in size

poikilocytosis

variation in shape

what causes acanthocytes?

alcoholic liver disease

what causes echinocytes?

liver disease, peptic ulcers

what causes elliptocytes?

hereditary elliptocytosis

what causes schistocytes?

mechanical damage, intravascular hemolysis

what causes blister cells?

vacuole bubbles

what causes helmet cells?

vacuole bursts

what causes drepanocytes?

sickle cell disease (polymerization of HgbS)

what causes spherocytes?

severe burns, Hereditary spherocytosis

what causes stomatocytes?

hereditary stomatocytosis, lead intoxication

what causes codocytes?

renal disease

what causes dacryocytes?

myelopthisic anemia

what are howell jolly bodies composed of?

DNA

what causes howell jolly bodies?

severe anemia, post splenectomy

what is basophilic stippling composed of and what causes them?

RNA, lead poisoning

what are cabot rings composed of and what causes them?

mitotic spindle, severe anemia

What are pappenheimer bodies composed of and what causes them?

Iron, severe anemia

What are heinz bodies composed of and what causes them?

denatured hemoglobin, post splenectomy and unstable hemoglobin disorders