Renal Meds

What is the MOA for phosphate binders?

Bind phosphate in GI tract -> prevents phosphate absorption in patients with CKD

What is the MOA for potassium binders?

Exchanges Na+ for K+ in colon -> excretes potassium in stool

What is the MOA for erythropoiesis-stimulating agents (ESA)?

Stimulates bone marrow to produce red blood cells

What is the MOA for vitamin D analogs?

Active form of vitamin D -> promotes calcium absorption, suppresses PTH

What are the nursing considerations for phosphate binders?

Give with meals; monitor phosphate and calcium levels; risk for hypocalcemia (Sevelamer)

What are the nursing considerations for potassium binders?

Monitor K+, bowel sounds (can cause necrosis); hold if hypoactive bowel; expect diarrhea

What are the nursing considerations for erythropoiesis-stimulating agents (ESA)?

Treats anemia of CKD; monitor Hgb (hold if >11 increase stroke), BP (may increase), iron stores

What are the nursing considerations for vitamin D analogs?

Monitor for hypercalcemia; needed in CKD for bone protection

Sevelamer and Calcium acetate are the generic names for what drug class?

phosphate binders

Sodium polystyrene sulfonate is the generic name for what drug class?

potassium binders

Epoetin alfa and Darbepoetin alfa are the generic names for what drug class?

erythropoiesis-stimulating agents (ESA)

Calcitriol is the generic name for what drug class?

vitamin D analogs